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pramoxine topical (OTC)Brand and Other Names:Itch-X Gel, Itch-X Spray, more...PrameGel, Prax, Sarna Sensitive Anti-Itch, proctoFoam, Azo Itch Relief Maximum Strength Analgesic Cream, Eczemin

 
 
 

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

topical cream

  • 1%

topical gel

  • 1%

topical lotion

  • 1%

topical spray

  • 1%
more...

Topical Pain

Apply to affected area up to 3-4 times/day

Feminine Itching

Apply small amount to external vaginal area up to 4 times/day

Dosage Forms & Strengths

topical cream

  • 1%

topical gel

  • 1%

topical lotion

  • 1%

topical spray

  • 1%
more...

Topical Pain

<2 years: Safety and efficacy not established

>2 years: Apply to affected area up to 3-4 times/day

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Adverse Effects

Frequency Not Defined

Irritation

Pruritus

Contact dermatitis

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Warnings

Contraindications

Hypersensitivity

Cautions

Do not exceed daily recommended dosage

Do not use in eyes or nose

Do not apply to large areas of body

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Pregnancy & Lactation

Pregnancy category: C

Lactation: Unknown if excreted in breast milk; exercise caution

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Mechanism of Action

Local anesthetic; stabilizes neuronal membranes and prevent generation/conduction of nerve impulses by reducing sodium permeability and increasing action potential threshold

Absorption

Onset: 32-5 min

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