attapulgite (Discontinued)Brand and Other Names:Kaopectate Maximum Strength, Diasorb, more...K-Pek

 
 
 

Dosing & Uses

AdultPediatricGeriatric

Dosage Forms & Strengths

liquid

  • 750mg/15mL

tablet

  • 600mg
more...

Diarrhea

1.2-1.5 g PO after each loose bowel movement; no more than 8.4 g/24 hours

Dosage Forms & Strengths

tablet

  • 600mg

liquid

  • 750mg/15mL
more...

Diarrhea

3-6 years old: 300 mg PO after each loose bowel movement; no more than 2.1 g/24 hours

6-12 years old: 600-750 mg PO after each loose bowel movement; no more than 4.5 g/24 hours

>12 years old: 1.2-1.5 g PO after each loose bowel movement; no more than 8.4 g/24 hours

Diarrhea

1.2-1.5 g PO after each loose bowel movement; no more than 8.4 g/24 hours

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Interactions

Interaction Checker

attapulgite and

No Results

     
     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Bloating

            Dyspepsia

            Flatulence

            Mild constipation

            Nausea

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            Warnings

            Contraindications

            Hypersensitivity, bowel obstruction, high fever (r/o infectious diarrhea), dysentery, blood in stool, bleeding ulcers, gout, hemophilia, hemorrhagic states

            Cautions

            In the US, Kaopectate has been reformulated to bismuth subsalicylate

            Avoid use in children <3 years

            Do not use for >2 days

            Take 2-3 hr before/after other drugs

            Elderly, diabetes

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            Pregnancy & Lactation

            Pregnancy Category: NA; not absorbed; unlikely to pose any risk during pregnancy

            Lactation: no data available; not absorbed; unlikely to pose any risk for nursing

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            Absorbent action, absorbs fluid in intestine and reduces stool liquidity

            Pharmacokinetics

            Onset: 12-19.5 hr

            Metabolism: Not absorbed from GI tract

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