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mineral oil (OTC)Brand and Other Names:Kondremul Plain

 
 
 

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

liquid

  • 100%
more...

Constipation

15-45 mL/day PO, single or divided doses

Kondremul: 30-75 mL/day

Dosage Forms & Strengths

liquid

  • 100%
more...

Constipation

<6 years

  • 15-30 mL/year of age; not to exceed 240 mL/day

6-12 years

  • 5-15 mL/day divided qDay, single or divided doses
  • Kondremul: 10-25 mL/day

>12 years

  • 15-45 mL/day PO, single or divided doses
  • Kondremul: 30-75 mL/day
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Interactions

Interaction Checker

mineral oil and

No Results

     
     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Lipid pneumonitis if reclined

            Incontinence of feces

            Intestinal malabsorption

            Impaired absorption of fat-soluble vtiamins

            Rectal discharge

            Anal pruritus and irritation

            Abdominal cramps

            Nausea

            Vomiting

            Lipid pneumonitis with aspiration

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            Warnings

            Contraindications

            Abdominal pain, nausea, vomiting, or other symptoms of appendicitis or acute surgical abdomen

            Fecal impaction, intestinal obstruction or perforation, colostomy, ileostomy, ulcerative colitis, diverticulitis

            Bedridden, geriatric, debilitated, or pregnant pts

            Patients with esophageal or gastric retention, dysphagia, or hiatal hernia

            Cautions

            Conditions that interfere with swallowing or epiglottal function may increase risk of aspiration, which can result in lipid penumonitis

            Do not admin. >1 wk

            Aspiration risk increases in the elderly

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            Pregnancy & Lactation

            Pregnancy Category: Not recommended (no FDA risk factor assigned)

            Lactation: Not known if excreted in breast milk; not recommended

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            Emollient; retards colonic absorption of water; decreases water absorption and lubricates intestine, which eases passage of stool

            Pharmacokinetics

            Onset of action: 6-8 hr (PO)

            Distribution: Colon

            Excretion: Feces

            Absorption: minimal

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