potassium acid phosphate (Rx)Brand and Other Names:KPhos Original, NeutraPhos

 
 
 

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

tablet

  • 500mg
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Elevated Urinary pH

1-2 tabs (500-1000mg) dissolved in 6-8 oz of water; take PO four times daily with meals and at bedtime

Safety and efficacy not established

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Interactions

Interaction Checker

potassium acid phosphate and

No Results

     
     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Diarrhea

            Nausea/vomiting

            Stomach pain

            Flatulence

            Bradycardia

            Hyperkalemia

            Local tissue necrosis with extravasation

            Weakness

            Dyspnea

            Hypocalcemia

            Tetany

            Phosphate intoxication

            Hypotension

            Arrhythmia

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            Warnings

            Contraindications

            Hyperphosphatemia, severe renal impairment, hyperkalemia, infected phophate stones

            Cautions

            May cause hyperkalemia; use caution in patients who require regulation of serum potassium concentrations

            Patients may experience mild laxative effects within first few days of therapy

            Use caution in patients with severe adrenal insufficiency, cardiac disease, myotonia congenita, pancreatitis, parathyroid disease, renal calculi, renal impairment, tissue breakdowns (burns), or rickets

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: Use with caution

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            Intracellular cation essential in physiological processes including transmission of nerve impulses, glucose utilization, muscle contractions, and enzyme activity

            Acidifies urine

            Pharmacokinetics

            Distribution: Enters cells from extracellular fluid via active transport

            Absorption: Well absorbed from upper GI tract

            Excretion: Urine (primarily); skin and feces (small amount)

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            Formulary

            FormularyPatient Discounts

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            Tier Description
            1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
            2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
            3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
            4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            NC NOT COVERED – Drugs that are not covered by the plan.
            Code Definition
            PA Prior Authorization
            Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
            QL Quantity Limits
            Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
            ST Step Therapy
            Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
            OR Other Restrictions
            Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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