Pau D'arco (Herbs/Suppl)

Brand and Other Names:La Pacho, Tabebuia avellanedae
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Suggested Dosing

1-4 g/d div BID-TID, use not more than 7d

1 tsp bark steeped in boiling water, 2-8 x/day

Dose based on lapachol content; lapachol intake should be 1.5-2.0 g/day

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Suggested Uses

Antimicrobial, especially anti-Candida

Claimed to be anti-cancer

Efficacy

Insufficient reliable data available

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Interactions

Interaction Checker

and Pau D'arco

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Nausea

            Vomiting

            Dizziness

            Anti-coagulant effects (reduced by using whole bark)

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            Warnings

            Contraindications

            N/A

            Cautions

            Products highly variable in lapachol content

            Negative anti-cancer results found by NCI based on isolated lapachol; whole bark contains synergistic compounds that reduce ADR's

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            Pregnancy & Lactation

            Pregnancy Category: N/A

            Lactation: N/A

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Metabolism: N/A

            Excretion: N/A

            Mechanism of Action

            Antimicrobial

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