Dosing & Uses
4 tablets PO q6hr, with liquid
Powder or Liquid
2 TBS PO q12hr x 3-4 days, then 1-2 TBS HS, 8 oz of fluid taken with each dose
Other Indications & Uses
Not recommended in children
Powder or liquid
1-2 TBS in milk or cereal PO qDay or q12hr x 3-4 days, then 1-2 TBS HS, 8 oz of fluid taken with each dose
>1 Month Old
1-2 teaspoonful in a single feeding
Serious - Use Alternative
Significant - Monitor Closely
Frequency Not Defined
Excessive bowel activity
Hypersensitivity, nausea/vomiting, bowel obstruction, appendicitis, dysphagia, fecal impaction, rectal bleeding
Rule out GI obstruction/perforation before administration
Caution with severe active ulcerative colitis
Pregnancy & Lactation
Pregnancy Category: B
Lactation: no data available; not absorbed, therefore it is unlikely to pose the risk in breast-feeding
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Bulk producing laxative
Onset: 12-72 hr
Metabolism: hydrolized in the colon, absorbed and then metabolized in the liver