Taurine (Herbs/Suppl)

Brand and Other Names:mega taurine
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Suggested Dosing

Congestive Heart Failure

2-6 g/day PO div BID-TID

Acute Hepatitis

4 g PO TID x 6 weeks

Treatment of Steatorrhea in Children with Cystic Fibrosis

30 mg/kg day x 4 months in addition to pancreatic enzyme supplementation

Cystathionine Beta-Synthase Deficient Homocystinuria (Orphan)

Indicated for treatment of cystathionine beta-synthase deficient homocystinuria

Orphan indication sponsor

  • Johan L. Van Hove, MD, PhD; Department of Pediatrics/University of Colorado DE; 13121 E. 17th Ave; PO Box 6508; Aurora, CO 80045
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Suggested Uses

CHF, hypertension, hypercholesterolemia, cystic fibrosis, antiatherogenic effects

Other uses include seizure disorders (epilepsy), autism, ADHD, retinal degeneration, diabetes, alcoholism, improve mental performance & antioxidant.

Efficacy

In human clinical studies taurine lowered blood pressure

CHF: Seems to improve left ventricular function in patients with New York Heart Association functional class II to IV

Acute Hepatitis: Might improve liver function

In animal studies taurine lowered lipid levels, but human studies are contradictory

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Interactions

Interaction Checker

and Taurine

No Results

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    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            None reported

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            Warnings

            Contraindications

            Hypersensitivity

            Cautions

            Pregnancy, lactation

            Monitor pts with CHF

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            Pregnancy & Lactation

            Pregnancy Category: avoid use

            Lactation: avoid use

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Metabolism: liver

            Excretion: feces & urine

            Mechanism of Action

            Antioxidant, putative hypocholesterolemic, hypotensive, antiatherogenic & detoxifying activities

            May also have steatorrhea-reducing activity in pts with cystic fibrosis & putative antidiabetic, inotropic & antiseizure activities

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