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magnesium chloride (Rx)Brand and Other Names:MgCl or MgCl(2)

 
 
 

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

injectable solution

  • 200mg/mL

tablet extended release

  • 535mg (64mg elemental)
more...

RDA (Elemental Magnesium)

Males: 400-420 mg PO qDay

18-30 (Females)

  • 310 mg PO qDay
  • Pregnancy: 350 mg PO qDay
  • Lactation: 310 mg PO qDay

>30 years (Females)

  • 320mg/day
  • Pregnant women: 360 mg/day
  • Lactating women: 320 mg/day

Hypomagnesemia

4 g (in 250 mL D5W) IV infusion; no more than 3 mL/min

Usual Range: 1- 40 g IV qDay

Use serum levels as guide to continue therapy

Dosage Forms & Strengths

injectable solution

  • 200mg/mL

tablet extended release

  • 535mg (64mg elemental)
more...

RDA

<6 months: 30 mg/day

6-12 months: 75 mg/day

1-3 years: 80 mg/day

3-8 years: 130 mg/day

8-13 years: 240 mg/day

13-18 years: 410 mg/day (men); 360 mg/day (women); 400 mg/day (pregnant women); 360 mg/day (lactating women)

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Interactions

Interaction Checker

magnesium chloride and

No Results

     
     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Respiratory depression

            Hypothermia

            Flushing

            Significant decrease in blood pressure

            Stupor

            Sweating

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            Warnings

            Contraindications

            Renal impairment

            Significant myocardial disease

            Comatose patients

            Cautions

            Administer with caution if flushing & sweating occurs

            Keep Ca salt antidote for IV injection ready

            Risk of developing respiratory paralysis if long tendon reflux is not present

            Contains benzyl alcohol (toxic in children)

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: Excreted in breast milk; use caution

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

            more...
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            Pharmacology

            Mechanism of Action

            Acts as cofactor in numerous enzymatic reactions involving protein synthesis and carbohydrate metabolism; depresses CNS, blocks peripheral neuromuscular transmission, produces anticonvulsant effects

            Pharmacokinetics

            Distribution: 50-60% (Bone ); 1-2% (extracellular fluid)

            Protein binding: 30% (albumin)

            Excretion: Urine (as magnesium)

            Absorption: Inversely proportional to amount ingested (15-36% at thigh doses and 40-60% at controlled dietary levels)

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            Administration

            IV Preparation

            4 g diluted in 250 mL D5W

            10 g multidose vial

            IV Administration

            NMT 3 mL/min

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            Images

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            Formulary

            FormularyPatient Discounts

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            The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

            Tier Description
            1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
            2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
            3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
            4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            NC NOT COVERED – Drugs that are not covered by the plan.
            Code Definition
            PA Prior Authorization
            Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
            QL Quantity Limits
            Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
            ST Step Therapy
            Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
            OR Other Restrictions
            Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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