neomycin/polymyxin B/ bacitracin/pramoxine (OTC)

Brand and Other Names:Neosporin Plus Pain Relief Ointment, TriBiozene Ointment
  • Print

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

neomycin/polymyxin B/bacitracin/pramoxine

topical ointment

  • (3.5mg/10,000units/500units/10mg)/g
more...

Skin Infection Prevention

Apply small amount to cleansed wound 1-3 times/day; not to exceed 1week

Dosage Forms & Strengths

neomycin/polymyxin B/bacitracin/pramoxine

topical ointment

  • (3.5mg/10,000units/500units/10mg)/g
more...

Skin Infection Prevention

Apply small amount to cleansed area 1-3 times/day; not to exceed 1week

Next:

Adverse Effects

Frequency Not Defined

Allergic contact dermatitis

Previous
Next:

Warnings

Contraindications

Hypersensitivity

Cautions

Ototoxicity and nephrotoxicity possible if treating large surface area or chronic use

Previous
Next:

Pregnancy & Lactation

Pregnancy category: C

Lactation: unknown if neomycin, polymyxin B, or bacitracin excreted in breast milk; systemic absorption of topical lidocaine has been reported

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

more...
Previous
Next:

Pharmacology

Mechanism of Action

Neomycin, polymyxin B, and bacitracin elicit bacteriostatic activity

Pramoxine provides local anesthetic effect

Previous
Next:

Images

Previous
Next: