phenylephrine nasal (OTC)

Brand and Other Names:NeoSynephrine Nasal, Neo-Synephrine Cold & Sinus Mild Strength Spray
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

nasal spray

  • 0.125%
  • 0.25%
  • 0.5%
  • 1%
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Nasal Congestion

Instill 2-3 sprays or 2-3 gtt q4hr of 0.25-0.1% solution PRN; not to exceed 3 days

Dosage Forms & Strengths

nasal spray

  • 0.125%
  • 0.25%
  • 0.5%
  • 1%
more...

Nasal Congestion

<2 years

  • Consult a physician

2-6 years

  • 1-3 gtt intranasally q2-4hr of 0.125% solution PRN; not to exceed 3 days

6-12 years

  • 2-3 gtt intranasally q4hr of 0.25% solution PRN; not to exceed 3 days

>12 years old

  • Instill 1-2 sprays or 1-2 gtt intranasally q4hr of 0.25-0.1% solution PRN; not to exceed 3 days
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Interactions

Interaction Checker

and phenylephrine nasal

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Stinging

            Dryness

            Rebound congestion

            Sneezing

            Burning

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            Warnings

            Contraindications

            Cardiac disease (hypertension, HR, palpitations)

            Nonselective MAO inhibitors: Risk of hypertensive reaction

            Cautions

            Rebound congestion may occur

            Use caution in DM and hypertension

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: not known if excreted in breast milk

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            Alpha adrenergic agonist; stimulates alpha-adrenergic receptors in nasal conjunctiva and arterioles to produce vasoconstriction that results in nasal decongestion

            Pharmacokinetics

            Absorption: Minimal systemic

            Duration: 2.5 - 4 hr

            Onset: < 2 min

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