Nadh (Herbs/Suppl)

Brand and Other Names:nicotinamide adenine dinucleotide
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Suggested Dosing

Nutrition & Energy Enhancement

2.5-5 mg PO qDay-qODay

Alzheimer's Disease

10-15 mg PO qDay-qODay

Parkinson's Disease

10-15 mg PO qDay-qODay

Chronic Fatigue Syndrome

10-15 mg PO qDay-qODay

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Suggested Uses

Chronic fatigue syndrome, improving mental clarity, alertness, and concentration, depression, jet lag, hypertension

Parkinson's disease, Alzheimer's disease

Efficacy

Insufficient information; positive results only from pilot studies or open-label studies

Dementia: Ineffective for mild to mod dementia from Alzheimer's

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Adverse Effects

None reported

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Warnings

Contraindications

Hypersensitivity to any component of oral product

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Pregnancy & Lactation

Pregnancy Category: N/A

Lactation: N/A

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

Coenzyme involved in ATP production (glycolysis, citric acid cycle, electron transport chain)

May increase tyrosine hydroxylase-mediated dopamine production

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