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sodium stibogluconate (Rx)Brand and Other Names:Pentostam, stibogluconate sodium

 
 
 

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

injectable solution

  • 100mg Sb/mL
more...

Leishmaniasis (Orphan)

20 mg Sb/kg/day (maximum 850 mg) IV/IM x20-28 days 

Available in the United States only from CDC

Dosage Forms & Strengths

injectable solution

  • 100mg Sb/mL
more...

Leishmaniasis

20 mg Sb/kg/day (maximum 850 mg) IV/IM x20-28 day 

Available in the United States only from CDC

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Adverse Effects

Frequency Not Defined

Anorexia

Nausea/vomiting

Abdominal pain

ECG changes

Headache

Lethargy

Myalgia

Raised liver enzymes

Coughing and substernal pain

Anaphylaxis (rare)

Fever

Sweating

Flushing

Vertigo

Bleeding from nose or gum

Jaundice

Rash

Pain and thrombosis on intravenous administration, intramuscular injection also painful

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Warnings

Contraindications

Significant renal impairment; breast-feeding

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Pregnancy & Lactation

Pregnancy Category: unknown

Lactation: unknown

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

more...
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Pharmacology

Metabolism: unknown

Excretion: unknown

Mechanism of Action

Reduction in the fructose diphosphate and an inhibition of glycolysis

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Images

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Formulary

FormularyPatient Discounts

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

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  • View the formulary and any restrictions for each plan.
  • Manage and view all your plans together – even plans in different states.
  • Compare formulary status to other drugs in the same class.
  • Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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