Phosphatidylserine (Herbs/Suppl)

Brand and Other Names:
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Suggested Dosing

Alzheimer's Disease

100 mg PO TID

Senile Dementia & Cognitive/Memory Impairment

100 mg PO TID

ADHD in Children

200-300 mg PO qDay

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Suggested Uses

Depression, mental impairment in geriatric, ADHD

Efficacy

Human trials show benefit in memory impairment, dementia

May lose its effectiveness with extended use > 16 weeks

Insufficient information for depression

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Adverse Effects

Frequency Not Defined

None reported

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Warnings

Contraindications

N/A

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Pregnancy & Lactation

Pregnancy Category: N/A

Lactation: N/A

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

Major phospholipid in neuronal membranes

May increase acetylcholine release

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