polymyxin B ophthalmic (Discontinued)

Brand and Other Names:
  • Print

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

polymyxin B/trimethoprim

ophthalmic solution

  • 10,000units/1mg/1mL (10mL)
more...

Conjunctivitis/Blepharoconjunctivitis

1 drop in affected eye(s) q3hr for 7-10 days; not to exceed 6 drops/day in each eye treated

Dosage Forms & Strengths

ophthalmic solution

  • 10,000units/1mg/1mL (10mL)
more...

Conjunctivitis/Blepharoconjunctivitis

<2 months: Safety and efficacy not established

>2 months: 1 drop in affected eye(s) q3hr for 7-10 days; not to exceed 6 drops/day in each eye treated

Next:

Adverse Effects

Frequency Not Defined

Blurry vision

Hypersensitivity (including lid edema, itching, increased redness, tearing, and circumocular rash)

Local irritation (including increased redness, burning, stinging, and itching)

Previous
Next:

Warnings

Contraindications

Minor ocular irritation; hypersensitivity to any components of product

Previous
Next:

Pregnancy & Lactation

Pregnancy category: C

Lactation: Unknown whether drug is excreted into breast milk

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

more...
Previous
Next:

Pharmacology

Mechanism of Action

Bactericidal; causes leakage of bacterial membrane by binding to phospholipids

Previous
Next:

Images

Previous
Next: