Pygeum (Herbs/Suppl)

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Brand and Other Names:prunus africana, pygeum africanum

Suggested Dosing

BPH

75-200 mg/d PO standardized extract

Standardized extract contains 14% triterpenes, 0.5% n-docosanol

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Suggested Uses

BPH

Traditionally had been used for inflammation, kidney disease, urinary problems, malaria, stomachache, fever, difficult urination, fever, madness, prostate gland inflammation

Efficacy

Likely effective for BPH symptoms; possibly less effective than saw palmetto

Reduces the functional symptoms of BPH. Decreases nocturia by 19%, increases peak urine flow by 23%, and reduces residual urine volume by 24% in men with BPH

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Adverse Effects

Nausea, abd pain

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Warnings

Contraindications

Hypersensitivity

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Pregnancy & Lactation

Pregnancy Category: N/A

Lactation: N/A

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

Ferulic acid reduce prostatic cholesterol levels

Phytosterols inhib. prostaglandin synth.

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