75-200 mg/d PO standardized extract
Standardized extract contains 14% triterpenes, 0.5% n-docosanol
Traditionally had been used for inflammation, kidney disease, urinary problems, malaria, stomachache, fever, difficult urination, fever, madness, prostate gland inflammation
Likely effective for BPH symptoms; possibly less effective than saw palmetto
Reduces the functional symptoms of BPH. Decreases nocturia by 19%, increases peak urine flow by 23%, and reduces residual urine volume by 24% in men with BPH
Nausea, abd pain
Pregnancy & Lactation
Pregnancy Category: N/A
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Ferulic acid reduce prostatic cholesterol levels
Phytosterols inhib. prostaglandin synth.