Suggested Dosing

400-500 mg PO TID

Prostatitis: 500 mg PO BID

Cancer: 420-1400 mg/sq.meter IV bolus qWeek

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Suggested Uses

Seasonal allergy; prevention of diabetic cataracts; viral infections; CVD

Adjunctive therapy in cancer

Chronic prostatitis, interstitial cystitis

Efficacy

Possibly effective in treatment of nonbacterial chronic prostatitis, interstitial cystitis

Other uses mainly derived from animal studies

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Interactions

Interaction Checker

and Quercetin

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            PO: Headache

            PO: Paresthesia

            IV: Dyspnea

            IV: N/V

            IV: Nephrotoxicity (>945 mg/sq. meter)

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            Warnings

            Contraindications

            Sophretin, meletin

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            Pregnancy & Lactation

            Pregnancy Category: N/A

            Lactation: N/A

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Metabolism: N/A

            Excretion: N/A

            Mechanism of Action

            Flavonoid found in many foods; anti-inflammatory, antioxidant

            Inhibits aldose reductase in lens

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