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vitamin B2 (OTC)Brand and Other Names:riboflavin

 
 
 

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

capsule

  • 50mg
  • 400mg

tablet

  • 25mg
  • 50mg
  • 100mg
more...

RDA

Males: 1.3 mg/day

Females: 1.1 mg/day

Pregnant: 1.4 mg/day

Nursing: 1.6 mg/day

Riboflavin Deficiency

Supplementation is indicated for adults with riboflavin deficiency syndromes

6-30 mg/day PO in divided doses

Dosage Forms & Strengths

capsule

  • 50mg
  • 400mg

tablet

  • 25mg
  • 50mg
  • 100mg
more...

RDA

0-6 months: 0.3 mg/day

5-12 months: 0.4 mg/day

1-3 years: 0.5 mg/day

3-8 years: 0.6 mg/day

8-13 years: 0.9 mg/day

13-18 years: 1.3 mg/day (Male); 1 mg/day (Female)

Riboflavin Deficiency

<3 years: Not established

3-12 years: 3-10 mg/day PO in divided doses

≥12 years: 6-30 mg/day PO in divided doses

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Adverse Effects

Frequency Not Defined

Yellow orange urine

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Warnings

Contraindications

Hypersensitivity

Cautions

Pregnancy (doses >RDA)

Discuss use of drug and side effects with patients as it relates to treatment

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Pregnancy & Lactation

Pregnancy Category: A (within RDA); C (>RDA)

Lactation: Safe

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

more...
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Nutrition

Sources: beef liver, almonds, milk, dairy products, egg, fish, spinach

Function: participates in physiologic processes

Deficiency: (very rare): swelling of lining of mouth and nose, mouth and lip sores, inflammation of tongue, dermatitis, anemia

Reduced by: sunlight, alcohol

Toxicity: none known

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Pharmacology

Mechanism of Action

Component of flavoprotein enzymes, that are necessaryfor normal tissue respiration; plays a role in activation of pyridoxine and conversion of tryptophan to niacin

Pharmacokinetics

Absorption: Via GI tract; increases with food

Metabolism: Liver

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