Brand and Other Names:RID Shampoo, Klout Shampoo, more...Pronto Shampoo, RID Mousse, A-200 Shampoo, Tisit Gel, Tisit Lotion, Tisit Shampoo
- Classes: Scabicidal Agents
Dosing & Uses
Treatment of Head, Body, Pubic Lice
Apply to affected areas, leave on 10 min & wash
Do not exceed 2 consecutive applications within 24 hr
Retreat in 7-10 days
Amount to apply varies: See package insert
See package insert
Frequency Not Defined
Slight corneal erosion
Hypersensitivity, ragweed (Asteraceae family plants) hypersensitivity
Pregnancy & Lactation
Pregnancy Category: C
Lactation: no studies
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Pyrethrins are absorbed through intact skin when applied topically
Piperonyl butoxide reportedly is poorly absorbed through intact skin when applied topically
Mechanism of Action
Following absorption through the chitinous exoskeleton of arthropods, pyrethrins stimulate the nervous system, apparently by competitively interfering with cationic conductances in the lipid layer of nerve cells, thereby blocking nerve impulse transmissions
Piperonyl butoxide has little or no insecticidal activity but potentiates that of pyrethrins by inhibiting the hydrolytic enzymes responsible for pyrethrins' metabolism in arthropods