Dosing & Uses
Dosage Forms & Strengths
Male: Apply 1 mL of 2% or 5% solution to affected areas of scalp q12hr (qAM & qHS); no more than 2 mL in 24 hours
Female: Apply 1 mL of 2% solution to affected areas of scalp q12hr (qAM & qHS)
Hair growth may require 4 months of therapy
Safety & efficacy not established
Frequency Not Defined
Allergic contact dermatitis
Exacerbation of hair loss
Erythema at site of application
May see systemic effects (hypotension)
Hypersensitivity to drug or components
Once started, need to use indefinitely; hair growth should be apparent by 4 months
Can be easily removed from scalp; avoid contact with scalp once applied
Hair color may change
Use caution in patients with heart disease
Solution is flammable; keep away from fire or flame
Avoid contact with eyes
Not for use when infection, redness, inlfammation present
Pregnancy & Lactation
Pregnancy Category: C
Lactation: Following topical application of the drug is not known, but the drug has been shown to distribute into milk following oral administration in lactating women
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Acts at the level of the hair follicle, possibly involving direct stimulation of hair follicle epithelial growth; may increase cutaneous blood flow, and stimulate resting hair follicles