Schisandra (Herbs/Suppl)

Brand and Other Names:schisandra chinensis, wu wei zi, more...schizandra, schisandra sphenanthera
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Suggested Dosing

Concentration, Coordination, & Endurance

1.5-6 g/day fruit PO, OR

500-2000 mg/day standardized extract PO

Hepatitis

20 mg lignan content/day (equivalent to 1.5 g crude schisandra)

Other Information

Standardized to minimum 1.3% lignan content

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Suggested Uses

Adaptogen; immunostimulant; viral- or drug-induced hepatitis treatment

Efficacy

Thought to lower LFTs in hepatitis, and improving concentration, coordination, & endurance

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Interactions

Interaction Checker

and Schisandra

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Minor GI disturbances

            Urticaria

            CNS depression

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            Warnings

            Contraindications

            Hypersensitivity

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            Pregnancy & Lactation

            Pregnancy Category: X

            Lactation: N/A

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            Increase hepatic glutathione, glucose-6-phosphate

            Inhibits CYP3A and P-gp metabolic enzymatic pathways

            Antioxidant

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