sodium lactate (Rx)

Brand and Other Names:
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

infusion solution

  • 5 mEq/mL (560 mg/mL)
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Alkalinizing Agent

As directed by physician (based on severity of metabolic acidosis)

Dosage Forms & Strengths

infusion solution

  • 500mL
  • 1000mL
more...

Alkalinizing Agent

As directed by physician (based on severity of metabolic acidosis)

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Interactions

Interaction Checker

and sodium lactate

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     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Febrile response

            Injection site infections

            Phlebitis

            Thrombosis

            Extravasation

            Hypervolemia

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            Warnings

            Contraindications

            Not for lactic acidosis

            Hypernatremia or fluid retention

            CHF, shock, respiratory alkalosis or other conditions that increase lactate

            Cautions

            Significant hypokalemia may occur

            No advantage over sodium bicarbonate and is contraindicated in the treatment of lactic acidosis

            Avoid rapid administration and overdosage

            Excess administration may result in metabolic alkalosis

            Severe renal impairment, edema with sodium retention

            Not for correcting severe acidotic states

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: use caution

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            Lactate is converted into bicarbonate

            Pharmacokinetics

            Metabolism: lactate is converted in the liver into bicarbonate

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            Administration

            IV Administration

            NMT 300 mL/hr in adults

            Do not use plastic containers in series connections

            Use only non-vented set or vented set with vent closed

            IV Incompatibilities

            Additive: Na-bicarbonate

            Storage

            Store at 40°C or less

            Protect from extreme heat & freezing

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            Formulary

            FormularyPatient Discounts

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            The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

            Tier Description
            1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
            2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
            3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
            4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            NC NOT COVERED – Drugs that are not covered by the plan.
            Code Definition
            PA Prior Authorization
            Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
            QL Quantity Limits
            Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
            ST Step Therapy
            Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
            OR Other Restrictions
            Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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