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calcium carbonate (OTC)Brand and Other Names:Tums Chewy Delights, Tums Extra, more...Tums Freshers, Tums Kids, Tums Regular, Tums Smoothies, Tums Ultra, Children's Pepto

 
 
 

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

tablet, chewable

  • 500mg (Tums Regular, Tums Freshers)
  • 750mg (Tums Extra, Tums Kids, Tums Smoothies)
  • 1000mg (Tums Ultra)
  • 1177mg (Tums Chewy Delights)
more...

Antacid

Take at onset of GI distress

Tums Regular, Tums Freshers (500 mg): Chew 2-4 tablets; not to exceed 15 tabs/24 hr

Tums Smoothies (750 mg): Chew 2-4 tablets; not to exceed 10 tabs/24 hr

Tums Extra (750 mg): Chew 2-4 tablets; not to exceed 9 tabs/24 hr

Tums Ultra (1000 mg): Chew 2-3 tablets; not to exceed 7 tabs/24 hr

Tums Chewy Delights (1177 mg): Chew and swallow 2-3 chews; not to exceed 10 chews/24 hr

Not to exceed 7 g/day

Calcium Supplementation

1-1.2 g PO qDay or divided q6-12hr with meals

Recommended Dietary Allowance

19-50 years: 1 g/day PO

Females

  • >51 years: 1.2 g/day PO

Males

  • 51-70 years: 1 g/day PO
  • >71 years: 1.2 g/day PO

Dosing Considerations

Calcium carbonate (elemental calcium equivalent)

  • 400 mg (161 mg)
  • 500 mg (200 mg)
  • 750 mg (300 mg)
  • 1000 mg (400 mg)
  • 1177 mg (470 mg)

Hyperphosphatemia (Orphan)

Treatment of hyperphosphatemia in patients with end-stage renal disease

Orphan indication sponsor

  • R & D Laboratories, Inc; 4204 Glencoe Avenue; Marina Del Rey, CA 90292

Dosage Forms & Strengths

tablet, chewable

  • 400mg (Children's Pepto)
  • 500mg (Tums Regular, Tums Freshers)
  • 750mg (Tums Extra, Tums Kids, Tums Smoothies)
  • 1000mg (Tums Ultra)
  • 1177mg (Tums Chewy Delights)
more...

Antacid

Children's Pepto

  • <2 years (<11 kg): Safety and efficacy not established
  • 2-5 years (12-21 kg): 400 mg (1 tablet) PO PRN; not to exceed 3 tablets/day
  • 6-11 years (22-43 kg): 800 mg (2 tablets) PO PRN; not to exceed 6 tablets/day

Tums Kids

  • <2 years (<11 kg): Safety and efficacy not established
  • 2-4 years (11-21 kg): 375 mg (1/2 tablet) PO BID with meal
  • >4 years (22-43 kg): 750 mg (1 tablet) PO TID with meal

Recommended Dietary Allowance

Dosage expressed as elemental calcium

0-6 months: 200 mg/day PO

7-12 months: 260 mg/day PO

1-3 years: 700 mg/day PO

4-8 years: 1000 mg/day PO

9-18 years: 1300 mg/day PO

Dosing Considerations

Calcium carbonate (elemental calcium equivalent)

  • 400 mg (161 mg)
  • 500 mg (200 mg)
  • 750 mg (300 mg)
  • 1000 mg (400 mg)
  • 1177 mg (470 mg)
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Interactions

Interaction Checker

calcium carbonate and

No Results

     
     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Anorexia

            Constipation

            Flatulence

            Nausea

            Vomiting

            Hypercalcemia

            Hypophosphatemia

            Milk-alkali syndrome

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            Warnings

            Contraindications

            Hypersensitivity

            Hypercalciuria

            Renal calculi

            Hypophosphatemia

            Hypercalcemia

            Suspected digoxin toxicity

            Cautions

            Shake suspension well; chew tablets thoroughly

            Absorption impaired in achlorhydria

            Hypercalcemia and hypercalciuria may result from long-term use

            Advise patients to limit intake of oxalate-rich foods (soy; green, leafy vegetables; animal protein) to avoid reduced absorption through Ca-oxalate formation

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            Pregnancy & Lactation

            Pregnancy category: C

            Lactation: Safe; crosses the placenta; appears in breast milk

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

            more...
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            Pharmacology

            Mechanism of Action

            Antacid: Neutralizes gastric acidity

            Dietary supplement: Prevents or treats negative Ca balance; oral Ca supplements may protect against renal calculi formation by chelating with oxalate in gut and preventing its absorption

            Phosphate binder: Binds with dietary phosphate to form insoluble calcium phosphate, which is excreted in feces

            Absorption

            Bioavailability: 25-35%; food increases absorption 10-30%; antacid action dependent on gastric emptying time

            Peak plasma time: 20-60 min (fasting state); up to 3 hr (ingested 1 hr after meals)

            Distribution

            Protein bound: 45%

            Elimination

            Renal clearance: 50-300 mg/day

            Excretion: Feces, as unabsorbed calcium (80%); urine (20%)

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