pramoxine vaginal (OTC)

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Brand and Other Names:Vagisil Maximum Strength, Azo Itch Relief Maximum Strength Analgesic Wipes

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

vaginal wipes

  • 1%
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Feminine Itching

Apply to affected area up to 3-4 times/day

Safety and efficacy not established

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Adverse Effects

Frequency Not Defined

Irritation

Pruritus

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Warnings

Contraindications

Hypersensitivity

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Pregnancy & Lactation

Pregnancy category: C

Lactation: Unknown if excreted in breast milk

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Mechanism of Action

Local anesthetic; stabilizes neuronal membranes and prevent generation/conduction of nerve impulses by reducing sodium permeability and increasing action potential threshold

Absorption

Onset: 2-5 min

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Images

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