Close
New

Medscape is available in 5 Language Editions – Choose your Edition here.

 

hepatitis a vaccine inactivated (Rx)Brand and Other Names:Havrix, Vaqta

 
 
 

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

injection

  • 50 units/mL (Vaqta adult dose)
  • 1440 ELISA units/mL (Havrix adult dose)
more...

Hepatitis A Immunization

Indicated as active immunization against hepatitis A virus (HAV) for any person seeking protection, and persons with the following risks: men who have sex with men, IV or non-IV illicit drug abusers, chronic liver disease, international travelers, close contact with an international adoptee, persons working with HAV-infected primates or HAV in lab setting

2-dose vaccination series: 1 mL IM; separate the 2 doses by 6-18 months (ACIP guidelines); Havrix labeling states separating the dose by 6-12 months

Additional Information

Up-to-date vaccination schedules available at http://www.cdc.gov/vaccines/default.htm

Dosage Forms & Strengths

injection

  • 25 units/0.5 mL (Vaqta pediatric dose)
  • 720 ELISA units/0.5mL (Havrix pediatric dose)
more...

Hepatitis A Immunization

Indicated as routine vaccination for children at least 12 months of age (ACIP guidelines)

<12 months: Not indicated

Routine vaccination (2-dose series): 0.5 mL IM initiated at aged 12 through 23 months; separate the 2 doses by 6-18 months (ACIP guidelines); Havrix labeling states separating the dose by 6-12 months

Children who have received 1 dose before age 24 months, should receive a second dose 6-18 months after the first dose

Catch up schedule

  • For any person ≥2 yr who has not already received hepatitis A vaccine series, give 2 doses separated by 6-18 months if immunity against hepatitis A virus infection is desired
  • Minimum interval between the 2-dose series is 6 months
Next

Interactions

Interaction Checker

hepatitis a vaccine inactivated and

No Results

     
     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            Sort by :  
             activity indicator 
            Previous
            Next

            Adverse Effects

            Suspected adverse events after administration of any vaccine may be reported to Vaccine Adverse Events Reporting System (VAERS), 1-800-822-7967

            >10%

            Injection site tenderness (3-56%), erythema (1-22%), warmth (1-17%), swelling (9-11%)

            Irritability (11-36%)

            Anorexia (1-19%)

            Drowsiness (15-17%)

            Headache (1-16%)

            Fever > 100.4 F (9-11%)

            1-10%

            URI (1-10%)

            Otitis media (8%)

            Rhinorrhea (6%)

            Diarrhea (1-6%)

            Cough (1-5%)

            Rash (1-5%)

            Weakness/fatigue (4%)

            Vomiting (1-4%)

            Fever > 102 F (3%)

            Crying (2%)

            <1%

            Hematoma

            Incr. CPK

            Photophobia

            Vertigo

            Previous
            Next

            Warnings

            Contraindications

            Documented hypersensitivity

            Cautions

            First dose at least 2 wk before exposure to HAV

            Current exposure to HAV: may co-administer IG

            Previous
            Next

            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: not established

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

            more...
            Previous
            Next

            Pharmacology

            Mechanism of Action

            Attenuated strain of hepatitis A virus (HAV) which stimulates active immunity

            Onset: 4 wk

            Duration: unknown

            These products convey active immunity via stimulation of production of endogenously produced antibodies

            The onset of protection from disease is relatively slow, but duration is long lasting (years)

            Previous
            Next

            Images

            Previous
            Next

            Formulary

            FormularyPatient Discounts

            To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

            Adding plans allows you to:

            • View the formulary and any restrictions for each plan.
            • Manage and view all your plans together – even plans in different states.
            • Compare formulary status to other drugs in the same class.
            • Access your plan list on any device – mobile or desktop.

            The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

            Tier Description
            1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
            2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
            3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
            4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            NC NOT COVERED – Drugs that are not covered by the plan.
            Code Definition
            PA Prior Authorization
            Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
            QL Quantity Limits
            Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
            ST Step Therapy
            Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
            OR Other Restrictions
            Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
            Add or Remove Plans
            Plans for
            Select State:
            Non-Medicare PlansMedicare Plans

            Select a box to add or remove a plan.

            Select a class to view formulary status for similar drugs

            Additional Offers
            Email to Patient

            From:

            To:

            The recipient will receive more details and instructions to access this offer.

            By clicking send, you acknowledge that you have permission to email the recipient with this information.

            Email Forms to Patient

            From:

            To:

            The recipient will receive more details and instructions to access this offer.

            By clicking send, you acknowledge that you have permission to email the recipient with this information.

            Previous
             
             
             
            All material on this website is protected by copyright, Copyright © 1994-2016 by WebMD LLC. This website also contains material copyrighted by 3rd parties.