rimexolone ophthalmic (Rx)

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Brand and Other Names:Vexol

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

ophthalmic solution

  • 1%
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Postoperative Inflammation

2 gtts in affected eye QID, start 24hr after surgery x 2 weeks

Anterior Uveitis

1-2 gtts in affected eye Qhr during waking hours x 1 week, 1 gtts q2hr during waking hours x 1week (2nd week), then taper

Other Indications & Uses

Ocular corticosteroid, antiinflammatory agent

Effective in iritis, keratitis, conjunctivitis, and many ocular inflammatory diseases; bacterial and viral infections require concomitant antibacterial and antiviral coverage, respectively

Safety and efficacy not established

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Adverse Effects

Frequency Not Defined

Glaucoma

Cataract

Potentiate super infection

Slow wound healing

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Warnings

Contraindications

Hypersensitivity to any component of the formulation

Herpes simplex keratitis, herpes simplex keratitis dendritic, ocular fungal disease, ocular tuberculosis, ocular viral disease

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Pregnancy & Lactation

Pregnancy Category: C

Lactation: ophthalmic corticosteroids have not been reported to cause problems in nursing babies

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Absorption: following topical instillation of corticosteroids into the conjunctival sac, is absorbed into the aqueous humor, & systemic absorption occurs

Mechanism of Action

Synthetic nonfluorinated corticosteroid

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Formulary

FormularyPatient Discounts

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The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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