moxifloxacin ophthalmic (Rx)

Brand and Other Names:Vigamox, Moxeza
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

ophthalmic solution

  • 0.5%
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Bacterial Conjunctivitis

Moxeza: 1 drop instilled into affected eye(s) q12hr for 1 week

Vigamox: 1 drop instilled into affected eye(s) q8hr for 1 week

Dosage Forms & Strengths

ophthalmic solution

  • 0.5%
more...

Bacterial Conjunctivitis

Moxeza

  • <4 months: Safety and efficacy not established
  • >4 months: 1 drop instilled into affected eye(s) q12hr

Vigamox

  • <1 year: Safety and efficacy not established
  • >1 year: 1 drop instilled into affected eye(s) q8hr for 1 week
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Adverse Effects

1-10%

Conjunctivitis

Dry eye

Fever

Increased cough

Infection

Ocular discomfort

Ocular hyperemia

Ocular pain

Ocular pruritus

Otitis media

Pharyngitis

Rash

Rhinitis

Subconjunctival hemorrhage

Tearing

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Warnings

Contraindications

Hypersensitivity to quinolones or other components of formulation

Cautions

May result in overgrowth of nonsusceptible organisms, including fungi

Some patients may require slit-lamp biomicroscopy and fluorescein staining

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Pregnancy & Lactation

Pregnancy category: C

Lactation: Unknown whether drug is excreted in breast milk; use with caution

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Mechanism of Action

Fluoroquinolone antibiotic; bactericidal; inhibits DNA gyrase in susceptible organisms and also inhibits topoisomerase IV

Absorption

Peak plasma concentration: 2.7 ng/mL

AUC: 45 ng/hr/mL

Elimination

Half-life: 13 hr

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Formulary

FormularyPatient Discounts

Adding plans allows you to compare formulary status to other drugs in the same class.

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

Adding plans allows you to:

  • View the formulary and any restrictions for each plan.
  • Manage and view all your plans together – even plans in different states.
  • Compare formulary status to other drugs in the same class.
  • Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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