pantothenic acid (OTC)

Brand and Other Names:Vitamin B5
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

tablet

  • 100mg
  • 200mg
  • 500mg
more...

Recommended Daily Intake

Take with food if administered orally

Men & Women >14 years: 5 mg/day

Pregnant women: 6 mg/day

Lactating women: 7 mg/day

Dietary Supplement

5-10 mg PO qDay

Neurodegeneration (Orphan)

Penatothenate phosphate

Orphan designation for pantothenate kinase assoicated neurodegeneration (PKAN)

Sponsor

  • Retrophin, Inc; 777 Third Avenue, 22nd Floor; New York, NY 10017

Dosage Forms & Strengths

tablet

  • 100mg
  • 200mg
  • 500mg
more...

Recommended Daily Intake

Take with food if administered orally

<6 months: 1.7 mg/day

6-12 months: 1.8 mg/day

1-3 years: 2 mg/day

3 - 8 years: 3 mg/day

8 -13 years: 4 mg/day

13-18 years: 5 mg/day

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Interactions

Interaction Checker

and pantothenic acid

No Results

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    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Diarrhea

            Contact dermatitis

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            Warnings

            Contraindications

            Hypersensitivity

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            Pregnancy & Lactation

            Pregnancy Category: Not studied

            Lactation: Not studied

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Nutrition

            Sources: milk, lean beef, eggs, cabbage, broccoli, legumes

            Function: required for intermediary metabolism of carbohydrates, proteins, and lipids; precursor of coenzyme A which is required for acetylation (acyl-group activation) reactions in gluconeogenesis, in the release of energy from carbohydrates, the synthesis and degradation of fatty acids, and the synthesis of sterols and steroid hormones, porphyrins, acetylcholine, and other compounds; essential for normal epithelial function

            Deficiency: (rare) abd pain, vomiting, insomnia

            Toxicity: >10 g/day can cause diarrhea

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            Pharmacology

            Mechanism of Action

            Plays a role in the synthesis and maintenance of coenzyme A

            Pharmacokinetics

            Absorbed in the intestine

            Excretion: Urine

            Metabolism: Hydrolyzed in the intestine to coenzyme A

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            Images

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