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Latest Updates in Pharmacy

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  • Vitamin D Supplements May Improve Asthma Control in Children Vitamin D Supplements May Improve Asthma Control in Children An inverse correlation between low vitamin D levels and asthma control in children was reported in the Journal of Allergy and Clinical Immunology. Vitamin D supplementation may enhance corticosteroid responses, control atopy, and improve control of pediatric asthma.
  • Inhaled Glucocorticoids Are Generally Safe During Pregnancy Inhaled Glucocorticoids Are Generally Safe During Pregnancy A study of data from the Danish National Birth Cohort supports the use of inhaled glucocorticoid for asthma treatment during pregnancy. No association with offspring disease risk was found in most categories, except for offspring endocrine, metabolic, and nutritional disorders.
  • Glucocorticoids May Increase Suicide and Neuropsychiatric Risk Glucocorticoids May Increase Suicide and Neuropsychiatric Risk Systemic glucocorticoid use may increase the risk of suicidal behavior and neuropsychiatric disorders, according to a study in the American Journal of Psychiatry. A previous history of neuropsychiatric disorders or higher dosages of glucocorticoids seem to increase this risk.
  • FDA Approves First Quadrivalent Vaccine for Seasonal Influenza FDA Approves First Quadrivalent Vaccine for Seasonal Influenza A new vaccine to prevent seasonal influenza in people ages 2 years through 49 years has been approved by the U.S. Food and Drug Administration. FluMist Quadrivalent is the first influenza vaccine to contain four strains of the influenza virus, two influenza A strains and two influenza B strains.
  • Naltrexone Can Effectively Treat Heroin and Amphetamine Dependence Naltrexone Can Effectively Treat Heroin and Amphetamine Dependence Naltrexone was shown to be effective in fostering sobriety in heroin- and amphetamine-dependent outpatients in a 10-week randomized, double-blind, placebo-controlled trial. Naltrexone implants resulted in higher study retention, decreased drug use, and improved clinical conditions for the patients.
 

Drug Updates

  • insulin detemir (Levemir) Indication for type 1 diabetes mellitus expanded to include children aged 2 years or older
  • omeprazole/amoxicillin/clarithromycin (Omeclamox-Pak) New prepackaged drug regimen for eradicating Helicobacter pylori infection in adults with duodenal ulcer
  • pazopanib (Votrient) New indication for treatment of advanced soft tissue sarcomas
  • everolimus (Afinitor) New indication for treatment of noncancerous kidney tumors (renal angiomyolipomas) not requiring immediate surgery in patients with tuberous sclerosis complex
  • levofloxacin (Levaquin) New indication for plague (Yersinia pestis) in adults and children aged 6 months or older
  • taliglucerase alfa (Elelyso) First FDA-approved plant cell-based enzyme replacement therapy for type 1 Gaucher disease using genetically engineered carrot cells
  • avanafil (Stendra) New FDA-approved phosphodiesterase-5 enzyme inhibitor for erectile dysfunction
  • florbetapir F 18 (AMYViD) New FDA-approved radioactive diagnostic for PET brain imaging of beta-amyloid neuritic plaques in adults being evaluated for cognitive decline (including Alzheimer disease)
  • rotigotine (Neupro) New indications and dosage regimens for advanced stage idiopathic Parkinson disease and moderate-to-severe primary restless legs syndrome
  • beclomethasone, intranasal (QNASL) New dry powder intranasal corticosteroid indicated for seasonal or perennial allergic and nonallergic rhinitis
 
 

Advisory Board

  • David Chelmow, MD, Leo J Dunn Distinguished Professor of Obstetrics and Gynecology, Virginia Commonwealth University Medical Center
  • John Geibel, MD, DSc, MA, Professor of Surgery, Yale University School of Medicine
  • Lars Grimm, MD, MHS, Duke University Medical Center
  • Jules E Harris, MD, Clinical Professor of Medicine, University of Arizona College of Medicine at Tucson
  • Rick Kulkarni, MD, Editor-in-Chief, Medscape Reference, Harvard Medical School
  • David J Maron, MD, FACC, FAHA, Professor of Medicine and Emergency Medicine, Vanderbilt University School of Medicine
  • Arlen D Meyers, MD, MBA, Professor of Otolaryngology and Dentistry, University of Colorado School of Medicine
  • Thomas M Wheeler, MD, Harlan J Spjut Professor of Pathology, Professor of Urology, Baylor College of Medicine
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