OsteoarthritisReviews have questioned the quality of studies of stem cell therapy for knee osteoarthritis, citing high risk of bias, low quality of evidence, only modest improvement reported, and possible placebo effect.
Quiz: UrticariaAcute urticaria may be associated with life-threatening angioedema and/or anaphylactic shock. Do you know key aspects of presentation, workup, and treatment? Test your knowledge with this short quiz.
GoiterA study found that patients with symptomatic benign nodular goiter who underwent thyroidectomy experienced improvements in tracheal anatomy, inspiratory flow, and health-related quality of life.
Case: Age 14, Weakness & Dyspnea?A 14-year-old boy presents with a 10-day history of progressive weakness. The patient reports rhinorrhea, cough, and malaise approximately 3 weeks before admission. What's the diagnosis?
Recent Drug Updates
burosumab (Crysvita)FDA approves Mab that targets the phosphaturic hormone FGF23 associated with X-linked hypophosphatemia
fostamatinib (Tavalisse)FDA approves spleen tyrosine kinase (SYK) inhibitor for adults with chronic immune thrombocytopenia (ITP)
nivolumab (Opdivo)Indication for advanced renal cell carcinoma expanded for use in combination with ipilimumab in previously untreated patients
ipilimumab (Yervoy)New indication for advanced renal cell carcinoma in combination with nivolumab
fosaprepitant (Emend)IV dosage form approved for chemotherapy-induced nausea and vomiting in children aged 6 years or older
Gastric Cancer: Declining Incidence, Poor PrognosisAlthough gastric cancer has become far less common, most patients present with advanced disease and have poor outcomes. Do you know the diagnostic and treatment options for this potentially fatal malignancy?
Red, Hot, and Swollen Foot in Diabetes: Charcot or No?Charcot foot, a significant problem in patients with diabetic neuropathy, is a destructive process that can lead to instability, ulceration, and even amputation. Do you know how to recognize this challenging condition early and intervene promptly?
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