Estimate aortic valve area
The Gorlin Equation relies on the ratio of peak-to-peak instantaneous gradients. In mild-moderate stenosis the peak-to-peak gradient, does not reflect mean gradient however it is often close to mean gradient for severe stenosis. In low-flow states (CO < 2.5 L/min) as the Gorlin equation tends to overestimate the degree of stenosis.
The normal aortic valve area is 3-4 cm2. Symptoms tend to not be apparent until the AS is severe (<1cm2). If a patient presents with symptoms and the AVA is measured in the mild-moderate range alternative causes should be explored before attributing them to AS alone.
Robert O Bonow, Blase A Carabello et al.
Oh J, Seward JB, Tajik AJ.
Kern MJ.
Gorlin R, Gorlin SG.
The Gorlin Equation relies on the ratio of peak-to-peak instantaneous gradients. In mild-moderate stenosis the peak-to-peak gradient, does not reflect mean gradient however it is often close to mean gradient for severe stenosis. In low-flow states (CO < 2.5 L/min) as the Gorlin equation tends to overestimate the degree of stenosis.
The normal aortic valve area is 3-4 cm2. Symptoms tend to not be apparent until the AS is severe (<1cm2). If a patient presents with symptoms and the AVA is measured in the mild-moderate range alternative causes should be explored before attributing them to AS alone.
Robert O Bonow, Blase A Carabello et al.
Oh J, Seward JB, Tajik AJ.
Kern MJ.
Gorlin R, Gorlin SG.
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