Estimate aortic valve area
The Gorlin Equation relies on the ratio of peak-to-peak instantaneous gradients. In mild-moderate stenosis the peak-to-peak gradient, does not reflect mean gradient however it is often close to mean gradient for severe stenosis. In low-flow states (CO < 2.5 L/min) as the Gorlin equation tends to overestimate the degree of stenosis.
The normal aortic valve area is 3-4 cm2. Symptoms tend to not be apparent until the AS is severe (<1cm2). If a patient presents with symptoms and the AVA is measured in the mild-moderate range alternative causes should be explored before attributing them to AS alone.
Robert O Bonow, Blase A Carabello et al.
Circulation 2006;114;84-231
Oh J, Seward JB, Tajik AJ.
The Echo Manual 3rd edition. Lippincott, Williams, Wilkins. 2007
Kern MJ.
The Cardiac Catheterization Handbook 4th Edition. Mosby 2003
Gorlin R, Gorlin SG.
Am Heart J 41:1-29, 1951
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