ASDAS-CRP (Ankylosing Spondylitis Disease Activity Score)

Assess disease activity in Ankylosing Spondylitis.

The global unit selector only affects unanswered questions
1.Back Pain Severity? (Rate From 0-10)
2.Duration of Morning Stiffness? (Rate From 0-10)
3.Patient Global Assessment of Disease Activity? (Rate From 0-10)
4.Peripheral Pain/Swelling? (Rate From 0-10)
5.CRP?
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1. Back Pain Severity? (Rate From 0-10)

More Information

Ask "How would you describe the overall level of AS neck, back or hip pain you have had?"

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About this Calculator

The Ankylosing Spondylitis Disease Activity Score (ASDAS) is an index to assess disease activity in Ankylosing Spondylitis (AS).

The prefered score uses CRP, rather than ESR.

ASDAS-CRP = 0.12 x Back Pain + 0.06 x Duration of Morning Stiffness + 0.11 x Patient Global + 0.07 x Peripheral Pain/Swelling + 0.58 x Ln(CRP+1)

ASDAS-ESR = 0.08 x Back Pain + 0.07 x Duration of Morning Stiffness + 0.11 x Patient Global + 0.09 x Peripheral Pain/Swelling + 0.29 x √(ESR)

Back pain, patient global assessment, duration of morning stiffness and peripheral pain/swelling are all assessed on a numerical rating scale (from 0 to 10).

The 3 cut-offs selected to separate these states (figure 1) were: <1.3 between "inactive disease" and "moderate disease activity", <2.1 between "moderate disease activity" and "high disease activity", and >3.5 between "high disease activity" and "very high disease activity".

Cut-offs for improvement scores were: a change ≥1.1 units for "clinically important improvement" and a change ≥2.0 units for "major improvement".

References

Lukas C, Landewé R, Sieper J, Dougados M, Davis J, Braun J, van der Linden S, van der Heijde D.

Development of an ASAS-endorsed disease activity score (ASDAS) in patients with ankylosing spondylitis.

Annals of the Rheumatic Diseases 2009, 68 (1): 18-24

van der Heijde D, Lie E, Kvien TK, Sieper J, van den Bosch F, Listing J, Braun J, Landewé R.

ASDAS, a highly discriminatory ASAS-endorsed disease activity score in patients with ankylosing spondylitis.

Annals of the Rheumatic Diseases 2009, 68 (12): 1811-8

Machado P, Landewé R, Lie E, Kvien TK, Braun J, Baker D, van der Heijde D.

Ankylosing Spondylitis Disease Activity Score (ASDAS): defining cut-off values for disease activity states and improvement scores.

Annals of the Rheumatic Diseases 2011, 70 (1): 47-53

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