APRI (AST to Platelet Ratio Index)

Assess likelihood of fibrosis or cirrhosis non-invasively using AST and platelet count.

The global unit selector only affects unanswered questions
1.AST?
2.AST upper limit of normal?
3.Platelet Count?
Created by

1. AST?

U/L
Created by
0/3 completed

About this Calculator

The AST to Platelet Ratio Index (APRI) tool has been found to useful as a non-invasive index that correlates with liver biopsy findings of fibrosis and cirrhosis.

In a meta-analysis by Lin et al, it was found that in patients with hepatitis C, an APRI score greater than 1.0 had a sensitivity of 76% and specificity of 72% for predicting cirrhosis. In addition, it was found that an APRI score greater than 0.7 had a sensitivity of 77% and specificity of 72% for predicting significant hepatic fibrosis.

References

Lin ZH, Xin YN, Dong QJ, et al.

Performance of the aspartate aminotransferase-to-platelet ratio index for the staging of hepatitis C-related fibrosis: an updated meta-analysis.

Hepatology: Official Journal of the American Association for the Study of Liver Diseases 2011, 53 (3): 726-36

Legal Notices and Disclaimer

© 2020 QxMD Software Inc., all rights reserved. No part of this service may be reproduced in any way without express written consent of QxMD. This information should not be used for the diagnosis or treatment of any health problem or disease. This information is not intended to replace clinical judgment or guide individual patient care in any manner. Click here for full notice and disclaimer.