Crohn's Disease Activity Index (CDAI)

Assess disease activity in Crohn's disease

The global unit selector only affects unanswered questions
1.Average Number of Liquid or Soft Stools per Day (over 7 days)?
2.Using Diphenoxylate or Loperimide for Diarrhea?
3.Average Abdominal Pain Rating (over 7 days)?
4.General Well Being each Day (over 7 days)?
5.Arthritis or Arthralgia?
6.Iritis or Uveitis?
7.Erythema Nodosum, Pyoderma Gangrenosum or Aphthous Stomatitis?
8.Anal Fissure, Fistula or Abscess?
9.Other Fistula?
10.Fever?
11.Abdominal mass?
12.Hematocrit?
13.Sex?
14.Current Weight?
15.Baseline Weight?
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1. Average Number of Liquid or Soft Stools per Day (over 7 days)?

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About this Calculator

The Crohn's Disease Activity Index (CDAI) is utilized in clinical trials to assess disease activity in Crohn's.

CDAI scores can range from 0 to ~600.

A cut-off value of <150 was selected so that most patients below this threshold would be rated by physicians as 'very well'.

The delineator between active and very severe disease was defined as a cut-off value of 450 points.

CDAI scores of 150–219 has been labelled as mildly active disease and scores of 220–450 as moderately active disease.

CDAI has some limitations, which include:

  • interobserver variability
  • ratings of 'general well being' and 'intensity of abdominal pain' are subjective
  • stool frequency is based on a diary filled in by the patient for 7 days before evaluation which doesn't generally get done in routine clinical practice
  • it is not accurate in patients with fistulizing and stenosing disease
  • it is not useful in patients with previous extensive ileo-colonic resections or stoma

References

Best WR.

Predicting the Crohn's disease activity index from the Harvey-Bradshaw Index.

nflammatory Bowel Diseases 2006, 12 (4): 304-10

Best WR, Becktel JM, Singleton JW, Kern F Jr.

Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study.

Gastroenterology 1976, 70 (3): 439-44

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