Reduce the need for liver biopsy by identifying patients with non-alcoholic fatty liver disease likely or unlikely to have advanced fibrosis
The NAFLD fibrosis score is used to distinguish between patients with nonalcoholic fatty liver disease who have (F3-F4) and do not have (F0-F2) advanced fibrosis.
This scoring system had an area under the ROC curve of 0.88 (95% CI 0.85-0.92).
The regression formula for prediction of severity of fibrosis is based on 6 variables: age (years), BMI(kg/m2), IFG/diabetes, AST/ALT ratio, platelet count and albumin (g/dl).
2 cutoff points were selected to identify the presence (> 0.676) and absence (< -1.455) of significant fibrosis.
Angulo P, Hui JM, Marchesini G et al.
The NAFLD fibrosis score is used to distinguish between patients with nonalcoholic fatty liver disease who have (F3-F4) and do not have (F0-F2) advanced fibrosis.
This scoring system had an area under the ROC curve of 0.88 (95% CI 0.85-0.92).
The regression formula for prediction of severity of fibrosis is based on 6 variables: age (years), BMI(kg/m2), IFG/diabetes, AST/ALT ratio, platelet count and albumin (g/dl).
2 cutoff points were selected to identify the presence (> 0.676) and absence (< -1.455) of significant fibrosis.
Angulo P, Hui JM, Marchesini G et al.
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