Estimate risk of advanced chronic kidney disease after acute kidney injury
This risk calculator was derived using over 9,000 patients with baseline eGFR ≥45 mL/min/1.73m² who were hospitalized in Alberta, Canada with acute kidney injury (AKI), and was used to predict advanced CKD (sustained eGFR < 30 mL/min/1.73m²) in the subsequent year after discharge from hospital. The models were internally validated in a cohort from Alberta, Canada, and externally validated in a cohort from Ontario, Canada.
Discharge serum creatinine (Scr) is categorized into 5 levels
Acute kidney injury (AKI) severity is determined by comparing peak serum creatinine during hospitalization with baseline creatinine according to the Kidney Disease Improving Global Outcomes (KDIGO) criteria.
AKI stage 1 if Scr increased by ≥0.3 mg/dL (≥26 μmol/L) or peak Scr was 1.5-1.9 times baseline Scr
AKI stage 2 if peak Scr is 2.0-2.9 times baseline Scr
AKI stage=3 if peak Scr ≥3.0 times baseline or peak Scr increased to ≥4.0 mg/dL (≥354 μmol/L), or a patient is treated with dialysis during hospitalization.
Albuminuria is categorized as
MT James, N Pannu, BR Hemmelgarn, PC Austin, Z Tan, E McArthur, BJ Manns, M Tonelli, R Wald, RR Quinn, P Ravani, Garg AX.
This risk calculator was derived using over 9,000 patients with baseline eGFR ≥45 mL/min/1.73m² who were hospitalized in Alberta, Canada with acute kidney injury (AKI), and was used to predict advanced CKD (sustained eGFR < 30 mL/min/1.73m²) in the subsequent year after discharge from hospital. The models were internally validated in a cohort from Alberta, Canada, and externally validated in a cohort from Ontario, Canada.
Discharge serum creatinine (Scr) is categorized into 5 levels
Acute kidney injury (AKI) severity is determined by comparing peak serum creatinine during hospitalization with baseline creatinine according to the Kidney Disease Improving Global Outcomes (KDIGO) criteria.
AKI stage 1 if Scr increased by ≥0.3 mg/dL (≥26 μmol/L) or peak Scr was 1.5-1.9 times baseline Scr
AKI stage 2 if peak Scr is 2.0-2.9 times baseline Scr
AKI stage=3 if peak Scr ≥3.0 times baseline or peak Scr increased to ≥4.0 mg/dL (≥354 μmol/L), or a patient is treated with dialysis during hospitalization.
Albuminuria is categorized as
MT James, N Pannu, BR Hemmelgarn, PC Austin, Z Tan, E McArthur, BJ Manns, M Tonelli, R Wald, RR Quinn, P Ravani, Garg AX.
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