Predict risk of rupture for asymptomatic intracranial aneurysms

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4.Size of aneurysm?
5.Earlier subarachnoid hemorrhage from another aneurysm?
6.Site of aneurysm?
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The PHASES score is an aid for prediction of the risk of rupture for asymptomatic intracranial aneurysms.

The score is based on a systematical review of six prospective cohort studies with subarachnoid hemorrhage as outcome. 8382 participants in the USA, Europe and Japan were included.

Several factors were independently associated with risk of rupture, including genetic background, age, hypertension, earlier SAH from another aneurysm, size and location of the aneurysm. A Cox proportional hazards model was generated based on these risk factors, resulting in an estimate of the absolute 5-years risk of rupture of an aneurysm.


Greving JP, Wermer MJH, Brown RD Jr, Morita A, Juvela S, Yonekura M, Ishibashi T, Torner JC, Nakayama T, Rinkel GJE, Algra A.

Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies.

Lancet Neurology 2014, 13 (1): 59-66

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