Multiple Sclerosis: Diagnosis

Diagnose MS using the 2017 McDonald Criteria

The global unit selector only affects unanswered questions
1.At least 1 distinct clinical attack? (Use caution if only using subjective history to define an attack.)
2.At least 2 distinct clinical attacks, involving different brain areas? (Use caution if only using subjective history to define an attack.)
3.T2 hyperintense lesions in two or more areas (juxtacortical/cortical, periventricular, infratentorial, and spinal cord)?
4.At least one of the MR lesions correlates with the clinical attack(s)?
5.At least two of the MR lesions correlate with the clinical attacks?
6.Positive Oligoclonal Bands on CSF?
Created by

1. At least 1 distinct clinical attack? (Use caution if only using subjective history to define an attack.)

Created by
0/6 completed

About this Calculator

The 2017 McDonald Criteria for Diagnosis of MS were compiled by the International Panel on Diagnosis of Multiple Sclerosis. Patients must meet criteria for dissemination in space (i.e, more than one brain/spinal cord area involved), and dissemination in time. An attack, when it consists only of worsening of previous symptoms in the context of a secondary cause (e.g. a fever or infection), should not be used to meet criteria. The main revisions from the 2010 McDonald Criteria are: symptomatic lesions can now be used to demonstrate dissemination in space or time in patients with supratentorial, infratentorial, or spinal cord syndrome, positive CSF oligoclonal bands can now be used to fulfill dissemination in time, and cortical lesions can now be utilized to demonstrate dissemination in space.

References

Thompson, A., Banwell, B., Barkhof, F., Carroll, W., Coetzee, T., Comi, G., Correale, J., Fazekas, F., Filippi, M., Freedman, M., Fujihara, K., Galetta, S., Hartung, H., Kappos, L., Lublin, F., Marrie, R., Miller, A., Miller, D., Montalban, X., Mowry, E., Sorensen, P., Tintoré, M., Traboulsee, A., Trojano, M., Uitdehaag, B., Vukusic, S., Waubant, E., Weinshenker, B., Reingold, S. and Cohen, J.

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria.

Lancet Neurology 2018, 17 (2): 162-173

Legal Notices and Disclaimer

© 2020 QxMD Software Inc., all rights reserved. No part of this service may be reproduced in any way without express written consent of QxMD. This information should not be used for the diagnosis or treatment of any health problem or disease. This information is not intended to replace clinical judgment or guide individual patient care in any manner. Click here for full notice and disclaimer.