Assess the need for neuroimaging in pediatric head trauma
The PECARN rule was developed to assist in decision making for neuroimaging in children with head trauma
Studies enrolled and analyzed 42412 children (derivation and validation totals 8502 and 2216 age <2 years and 25283 and 6411 ≥ 2 years respectively). The prediction rule had a negative predictive value of 100% (95% CI 99.7-100.0) and sensitivity of 100% (86.3-100.0) for clinically significant traumatic brain injury (cTBI) in children < 2 years of age. The prediction rule had a negative predictive value of 99.95% (99.81-99.99) and sensitivity of 96.8% (89.0-99.6) for clinically significant traumatic brain injury (cTBI) in children ≥ 2 years of age.
Kuppermann et al. have derived a clinical decision rule that has been externally validated to identify children with very low risk of cTBI. In these identified children, routine CT scanning is not necessary.
The risk of clinically significant traumatic brain injury is calculated as follows:
Variable & Associated Points
Absence of any of those features found < 0.02% of children had clinical significant traumatic brain injury on neuroimaging
Kuppermann, N., Holmes, J., Dayan, P., Hoyle, J., Atabaki, S., Holubkov, R., Nadel, F., Monroe, D., Stanley, R., Borgialli, D., Badawy, M., Schunk, J., Quayle, K., Mahajan, P., Lichenstein, R., Lillis, K., Tunik, M., Jacobs, E., Callahan, J., Gorelick, M., Glass, T., Lee, L., Bachman, M., Cooper, A., Powell, E., Gerardi, M., Melville, K., Muizelaar, J., Wisner, D., Zuspan, S., Dean, J. and Wootton-Gorges, S.
Schonfeld, D., Bressan, S., Da Dalt, L., Henien, M., Winnett, J. and Nigrovic, L.
The PECARN rule was developed to assist in decision making for neuroimaging in children with head trauma
Studies enrolled and analyzed 42412 children (derivation and validation totals 8502 and 2216 age <2 years and 25283 and 6411 ≥ 2 years respectively). The prediction rule had a negative predictive value of 100% (95% CI 99.7-100.0) and sensitivity of 100% (86.3-100.0) for clinically significant traumatic brain injury (cTBI) in children < 2 years of age. The prediction rule had a negative predictive value of 99.95% (99.81-99.99) and sensitivity of 96.8% (89.0-99.6) for clinically significant traumatic brain injury (cTBI) in children ≥ 2 years of age.
Kuppermann et al. have derived a clinical decision rule that has been externally validated to identify children with very low risk of cTBI. In these identified children, routine CT scanning is not necessary.
The risk of clinically significant traumatic brain injury is calculated as follows:
Variable & Associated Points
Absence of any of those features found < 0.02% of children had clinical significant traumatic brain injury on neuroimaging
Kuppermann, N., Holmes, J., Dayan, P., Hoyle, J., Atabaki, S., Holubkov, R., Nadel, F., Monroe, D., Stanley, R., Borgialli, D., Badawy, M., Schunk, J., Quayle, K., Mahajan, P., Lichenstein, R., Lillis, K., Tunik, M., Jacobs, E., Callahan, J., Gorelick, M., Glass, T., Lee, L., Bachman, M., Cooper, A., Powell, E., Gerardi, M., Melville, K., Muizelaar, J., Wisner, D., Zuspan, S., Dean, J. and Wootton-Gorges, S.
Schonfeld, D., Bressan, S., Da Dalt, L., Henien, M., Winnett, J. and Nigrovic, L.
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