Newborn Hyperbilirubinemia Assessment

Infant Age
Total Bilirubin
Clinical Risk Group Gestation >= 38 weeks and medically well (1)

Gestation >= 38 weeks but clinical risk factors (2)

Gestation 35-37.9 weeks and medically well (2)

Gestation 35-37.9 weeks and clinical risk factors (3)
  • Equation parameters such as Clinical Risk Group have two or more discrete values that may be used in the calculation. The numbers in the parentheses, e.g. (1), represent the values that will be used.
  • This nomogram derived calculator should only be used for infants of 35 weeks geastation or greater.
  • Data extracted from the Bhutani study include 36 week infants over 2000 gms and 25 week infants over 2500 gms birth weight.
  • These nomograms should NOT be be used to predict the natural history of hyperbilirubinemia.
  • Clinical risk factors include:
    1. Isoimmune hemolytic disease or G6PD deficiency
    2. Asphyxia or lethargy
    3. Unstable temperature, sepsis or acidosis
    4. Hypoalbuminemia (less than 3 gm/L, a risk factor when considering phototherapy, not transfusion)
  1. Bhutani VK, Johnson L, Sivieri EM. Predictive ability of a predischarge hour-specific serum bilirubin for subsequent significant hyperbilirubinemia in healthy term and near-term newborns. Pediatrics. 1999 Jan;103(1):6-14.
  2. American Academy of Pediatrics Subcommittee on Hyperbilirubinemia. Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics. 2004 Jul;114(1):297-316.
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