abicipar pegol (Pending FDA Approval)

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Dosing & Uses

AdultPediatric

Exudative Age-Related Macular Degeneration

Pending FDA approval for exudative (neovascular, wet) age-related macular degeneration (AMD)

Safety and efficacy not established

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Pharmacology

Mechanism of Action

Nonimmunoglobulin protein; designed ankyrin repeat protein (DARPin) that targets vascular endothelial growth factor- A (VEGF-A)

VEGF is a key mediator in ocular angiogenesis

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.