Suggested Dosing
No typical dosing guidelines
Suggested Uses
Antibacterial, antiviral, antifungal, antitumor, analgesic, hypotensive, antiinflamatory, & immune enhancing effect
Reduces total cholesterol & triglycerides
Reduction of chronic pain, painful inflammation & swelling (root extract)
Treatment of diabetes (chewing leaves releases & activates soluble dietary fiber): slows absorption of simple sugars from gut
Treatment of parasitic infections (extract from leaves of Morinda citrifolia) ie, intestinal nematodes
Anti-inflammatory & acne reduction when applied topically
Cancer: antitumor potential
Efficacy
There is insufficient reliable information available
Interactions
Interaction Checker
No Results
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
Contraindicated (0)
Serious - Use Alternative (0)
Monitor Closely (7)
- amiloride
amiloride and noni juice both increase serum potassium. Use Caution/Monitor.
- drospirenone
drospirenone and noni juice both increase serum potassium. Use Caution/Monitor.
- potassium acid phosphate
potassium acid phosphate and noni juice both increase serum potassium. Use Caution/Monitor.
- potassium chloride
potassium chloride and noni juice both increase serum potassium. Use Caution/Monitor.
- potassium citrate
potassium citrate and noni juice both increase serum potassium. Use Caution/Monitor.
- spironolactone
spironolactone and noni juice both increase serum potassium. Use Caution/Monitor.
- triamterene
triamterene and noni juice both increase serum potassium. Use Caution/Monitor.
Minor (88)
- acebutolol
acebutolol and noni juice both increase serum potassium. Minor/Significance Unknown.
- aceclofenac
aceclofenac and noni juice both increase serum potassium. Minor/Significance Unknown.
- acemetacin
acemetacin and noni juice both increase serum potassium. Minor/Significance Unknown.
- albuterol
noni juice increases and albuterol decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- arformoterol
noni juice increases and arformoterol decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- aspirin
aspirin and noni juice both increase serum potassium. Minor/Significance Unknown.
- aspirin rectal
aspirin rectal and noni juice both increase serum potassium. Minor/Significance Unknown.
- aspirin/citric acid/sodium bicarbonate
aspirin/citric acid/sodium bicarbonate and noni juice both increase serum potassium. Minor/Significance Unknown.
- atenolol
atenolol and noni juice both increase serum potassium. Minor/Significance Unknown.
- bendroflumethiazide
noni juice increases and bendroflumethiazide decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- betaxolol
betaxolol and noni juice both increase serum potassium. Minor/Significance Unknown.
- bisoprolol
bisoprolol and noni juice both increase serum potassium. Minor/Significance Unknown.
- bumetanide
noni juice increases and bumetanide decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- candesartan
candesartan and noni juice both increase serum potassium. Minor/Significance Unknown.
- carbenoxolone
noni juice increases and carbenoxolone decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- carvedilol
carvedilol and noni juice both increase serum potassium. Minor/Significance Unknown.
- celecoxib
celecoxib and noni juice both increase serum potassium. Minor/Significance Unknown.
- celiprolol
celiprolol and noni juice both increase serum potassium. Minor/Significance Unknown.
- chlorothiazide
noni juice increases and chlorothiazide decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- chlorthalidone
noni juice increases and chlorthalidone decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- choline magnesium trisalicylate
choline magnesium trisalicylate and noni juice both increase serum potassium. Minor/Significance Unknown.
- cyclopenthiazide
noni juice increases and cyclopenthiazide decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- diclofenac
diclofenac and noni juice both increase serum potassium. Minor/Significance Unknown.
- diflunisal
diflunisal and noni juice both increase serum potassium. Minor/Significance Unknown.
- digoxin
digoxin and noni juice both increase serum potassium. Minor/Significance Unknown.
- dobutamine
noni juice increases and dobutamine decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- dopexamine
noni juice increases and dopexamine decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- ephedrine
noni juice increases and ephedrine decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- epinephrine
noni juice increases and epinephrine decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- epinephrine racemic
noni juice increases and epinephrine racemic decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- eprosartan
eprosartan and noni juice both increase serum potassium. Minor/Significance Unknown.
- esmolol
esmolol and noni juice both increase serum potassium. Minor/Significance Unknown.
- ethacrynic acid
noni juice increases and ethacrynic acid decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- etodolac
etodolac and noni juice both increase serum potassium. Minor/Significance Unknown.
- fenoprofen
fenoprofen and noni juice both increase serum potassium. Minor/Significance Unknown.
- flurbiprofen
flurbiprofen and noni juice both increase serum potassium. Minor/Significance Unknown.
- formoterol
noni juice increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- furosemide
noni juice increases and furosemide decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- gentamicin
noni juice increases and gentamicin decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- hydrochlorothiazide
noni juice increases and hydrochlorothiazide decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- ibuprofen
ibuprofen and noni juice both increase serum potassium. Minor/Significance Unknown.
- indapamide
noni juice increases and indapamide decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- indomethacin
indomethacin and noni juice both increase serum potassium. Minor/Significance Unknown.
- irbesartan
irbesartan and noni juice both increase serum potassium. Minor/Significance Unknown.
- isoproterenol
noni juice increases and isoproterenol decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- ketoprofen
ketoprofen and noni juice both increase serum potassium. Minor/Significance Unknown.
- ketorolac
ketorolac and noni juice both increase serum potassium. Minor/Significance Unknown.
- ketorolac intranasal
ketorolac intranasal and noni juice both increase serum potassium. Minor/Significance Unknown.
- labetalol
labetalol and noni juice both increase serum potassium. Minor/Significance Unknown.
- levalbuterol
noni juice increases and levalbuterol decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- lornoxicam
lornoxicam and noni juice both increase serum potassium. Minor/Significance Unknown.
- losartan
losartan and noni juice both increase serum potassium. Minor/Significance Unknown.
- meclofenamate
meclofenamate and noni juice both increase serum potassium. Minor/Significance Unknown.
- mefenamic acid
mefenamic acid and noni juice both increase serum potassium. Minor/Significance Unknown.
- meloxicam
meloxicam and noni juice both increase serum potassium. Minor/Significance Unknown.
- metaproterenol
noni juice increases and metaproterenol decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- methyclothiazide
noni juice increases and methyclothiazide decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown. .
- metolazone
noni juice increases and metolazone decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- metoprolol
metoprolol and noni juice both increase serum potassium. Minor/Significance Unknown.
- nabumetone
nabumetone and noni juice both increase serum potassium. Minor/Significance Unknown.
- nadolol
nadolol and noni juice both increase serum potassium. Minor/Significance Unknown.
- naproxen
naproxen and noni juice both increase serum potassium. Minor/Significance Unknown.
- nebivolol
nebivolol and noni juice both increase serum potassium. Minor/Significance Unknown.
- norepinephrine
noni juice increases and norepinephrine decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- olmesartan
olmesartan and noni juice both increase serum potassium. Minor/Significance Unknown.
- oxaprozin
oxaprozin and noni juice both increase serum potassium. Minor/Significance Unknown.
- parecoxib
parecoxib and noni juice both increase serum potassium. Minor/Significance Unknown.
- penbutolol
penbutolol and noni juice both increase serum potassium. Minor/Significance Unknown.
- pindolol
pindolol and noni juice both increase serum potassium. Minor/Significance Unknown.
- pirbuterol
noni juice increases and pirbuterol decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- piroxicam
piroxicam and noni juice both increase serum potassium. Minor/Significance Unknown.
- propranolol
propranolol and noni juice both increase serum potassium. Minor/Significance Unknown.
- sacubitril/valsartan
sacubitril/valsartan and noni juice both increase serum potassium. Minor/Significance Unknown.
- salicylates (non-asa)
salicylates (non-asa) and noni juice both increase serum potassium. Minor/Significance Unknown.
- salmeterol
noni juice increases and salmeterol decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- salsalate
salsalate and noni juice both increase serum potassium. Minor/Significance Unknown.
- sotalol
sotalol and noni juice both increase serum potassium. Minor/Significance Unknown.
- succinylcholine
noni juice and succinylcholine both increase serum potassium. Minor/Significance Unknown.
- sulfasalazine
sulfasalazine and noni juice both increase serum potassium. Minor/Significance Unknown.
- sulindac
sulindac and noni juice both increase serum potassium. Minor/Significance Unknown.
- telmisartan
telmisartan and noni juice both increase serum potassium. Minor/Significance Unknown.
- terbutaline
noni juice increases and terbutaline decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- timolol
timolol and noni juice both increase serum potassium. Minor/Significance Unknown.
- tolfenamic acid
tolfenamic acid and noni juice both increase serum potassium. Minor/Significance Unknown.
- tolmetin
tolmetin and noni juice both increase serum potassium. Minor/Significance Unknown.
- tolvaptan
noni juice and tolvaptan both increase serum potassium. Minor/Significance Unknown.
- torsemide
noni juice increases and torsemide decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- valsartan
valsartan and noni juice both increase serum potassium. Minor/Significance Unknown.
Adverse Effects
Acute hepatitis, liver toxicity, liver damage, hyperkalemia
Warnings
Contraindications
History of hepatitis; liver disease
Cautions
Diarrhea: laxative effect
Liver damage, including liver transplant
Advanced kidney disease
Use smallest quantity
Pregnancy & Lactation
Pregnancy Category: N/A
Lactation: N/A
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Metabolism: N/A
Excretion: N/A
Mechanism of Action
Prevents carcinogen DMBA-DNA adduct formation & antioxidant activity contributes to cancer prevention effect
Synergistic effects when combined w/ a broad spectrum of chemotherapeutic drugs (cisplatin, 5-fl uorouracil, methotrexate)
Potentiates NK cell, macrophage, T-helper cell function
