Indication-specific dosing for actaea racemosa, baneberry, black snakeroot black cohosh in combination, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Sections

Sections Black Cohosh
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Suggested Dosing

Dried root: 300-2000 mg PO TID

Extract: 0.3-2 mL PO daily; 1:1, 90% alcohol

Tincture: 2-4 mL PO daily; 1:10, 60% alcohol

Tablet: 20-80 mg PO BID; standardized to 1 mg triterpene glycosides/20 mg tablet

Suggested Uses

Cough/sore throat, dysmenorrhea, dyspepsia, labor induction, menopausal symptoms, nervous tension, premenstrual syndrome, rheumatism

Efficacy

Likely effective for menopausal vasomotor symptoms

Possibly effective for PMS/dysmenorrhea

Interaction Checker

Enter a drug name and Black Cohosh

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No Interactions Found

Interactions Found

Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

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Frequency Not Defined

Cramping

Dizziness

GI upset

Headache

Sweating

Weight gain

Rash

Overdose: Bradycardia

CNS disturbances

Nausea/vomiting

Visual disturbances

Contraindications

Breast cancer, endometrial cancer, endometriosis, hormone sensitive conditions, ovarian cancer, pregnancy, lactation, uterine fibroids

Cautions

May be associated with liver damage

Pregnancy & Lactation

Pregnancy Category: unsafe

Lactation: unsafe

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

May act by blocking serotonin reuptake

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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