Dosing & Uses
Dosage Forms & Strengths
sodium citrate/citric acid (1 mEq sodium equivalent to 1 mEq bicarbonate)
oral solution
- (500mg/334mg)/5mL
- (490mg/640mg)/5mL
Urine Alkalinization, Prevention of Nephrolithiasis
10-30 mL diluted in up to 6 oz water/juice PO PC & HS PRN
Follow with additional water if desired
Dosage Forms & Strengths
sodium citrate/citric acid (1 mEq sodium equivalent to 1 mEq bicarbonate)
oral solution
- (500mg/334mg)/5mL
- (490mg/640mg)/5mL
Urine Alkalinization, Prevention of Nephrolithiasis
<2 years: Based on physician's discretion
≥2 years: 5-15 mL diluted in 30-90 mL of water/juice PO PC & HS PRN
Follow with additional water if desired
Interactions
Interaction Checker
No Results
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
Adverse Effects
Frequency Not Defined
Diarrhea
Nausea
Tetany
Metabolic alkalosis
Vomiting
Stomach pain
Fluid retention
Warnings
Contraindications
Hypersensitivity to drug or component of the formulation
Severe renal impairment
Sodium-restricted diet
Cautions
Use with caution in high BP, kidney or liver disease, cardiac failure, toxemia of pregnancy, peripheral/pulmonary edema, shock, or the severely ill
Do not dilute in tomato juice
Pregnancy & Lactation
Pregnancy Category: C
Lactation: consult physician
Pregnancy Categories
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Pharmacology
Mechanism of Action
Alkalinizes urine; citrate binds with urinary calcium
Pharmacokinetics
Metabolism: Oxidized to sodium bicarbonate
Excretion: Urine
Images
Patient Handout
Formulary
Adding plans allows you to compare formulary status to other drugs in the same class.
To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.
Adding plans allows you to:
- View the formulary and any restrictions for each plan.
- Manage and view all your plans together – even plans in different states.
- Compare formulary status to other drugs in the same class.
- Access your plan list on any device – mobile or desktop.
