hypochlorous acid topical (Rx)

Brand and Other Names:Alevicyn
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

Topical spray (Alevicyn Antimicrobial Dermal Spray)

  • Contains sodium chloride (NaCl), sodium sulfate (Na2SO4), monobasic sodium phosphate (NaH2PO4), and hypochlorous acid (HClO 90mg/L), and water

Topical gel (Alevicyn Antipruritic Gel)

  • Contains magnesium fluorosilicate, sodium phosphate, sodium chloride (NaCl), and hypochlorous acid (HClO), and water

Topical spray gel (Alevicyn Antipruritic SG)

  • Contains sodium lithium magnesium fluorosilicate, dimethicone, sodium phosphate (Na3PO4), sodium bicarbonate (NaHCO3), sodium chloride (NaCl), sodium sulfate (Na2SO4), hypochlorous acid (HClO), sodium hypochlorite (NaClO), and water

Cleansing and Debridement

Alevicyn Antimicrobial Dermal Spray: Used for cleansing, irrigation, moistening, debridement and removal of foreign material including microorganisms and debris from a variety of skin wounds

Spray to the affected topical area BID to irrigate and debride wounds, and periwound tissue

Uses include

  • Exudating wounds
  • Acute and chronic dermal lesions including stage I-IV pressure ulcers, stasis ulcers, diabetic ulcers, postsurgical wounds, first- and second-degree burns, abrasions, minor irritations of the skin, diabetic foot ulcers, ingrown toe nails, grafted/donor sites, and exit sites

Pruritus

Alevicyn Antipruritic SG

  • Indicated to manage and relieve the burning, itching and pain experienced with various types of dermatoses, including radiation dermatitis and atopic dermatitis
  • Apply to affected skin areas qDay or BID, or as needed, and massage gently into skin

Alevicyn Antipruritic Gel

  • Indicated for management of itch and pain associated with dermal irritations and wounds (eg, sores, injuries, and ulcers of dermal tissue)
  • Apply to affected skin areas qDay or BID and massage gently into skin; cover area with bandage if necessary

Dosage Forms & Strengths

Topical spray (Alevicyn Antimicrobial Dermal Spray)

  • Contains sodium chloride (NaCl), sodium sulfate (Na2SO4), monobasic sodium phosphate (NaH2PO4), and hypochlorous acid (HClO 90mg/L), and water

Topical gel (Alevicyn Antipruritic Gel)

  • Contains magnesium fluorosilicate, sodium phosphate, sodium chloride (NaCl), and hypochlorous acid (HClO), and water

Topical spray gel (Alevicyn Antipruritic SG)

  • Contains sodium lithium magnesium fluorosilicate, dimethicone, sodium phosphate (Na3PO4), sodium bicarbonate (NaHCO3), sodium chloride (NaCl), sodium sulfate (Na2SO4), hypochlorous acid (HClO), sodium hypochlorite (NaClO), and water

Cleansing and Debridement

Alevicyn Antimicrobial Dermal Spray: Used for cleansing, irrigation, moistening, debridement and removal of foreign material including microorganisms and debris from a variety of skin wounds

Spray to the affected topical area BID to irrigate and debride wounds, and periwound tissue

Uses include

  • Exudating wounds
  • Acute and chronic dermal lesions including stage I-IV pressure ulcers, stasis ulcers, diabetic ulcers, postsurgical wounds, first- and second-degree burns, abrasions, minor irritations of the skin, diabetic foot ulcers, ingrown toe nails, grafted/donor sites, and exit sites

Pruritus

Alevicyn Antipruritic SG

  • Indicated to manage and relieve the burning, itching and pain experienced with various types of dermatoses, including radiation dermatitis and atopic dermatitis
  • Apply to affected skin areas qDay or BID, or as needed, and massage gently into skin

Alevicyn Antipruritic Gel

  • Indicated for management of itch and pain associated with dermal irritations and wounds (eg, sores, injuries, and ulcers of dermal tissue)
  • Apply to affected skin areas qDay or BID and massage gently into skin; cover area with bandage if necessary
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Adverse Effects

Frequency Not Defined

Temporary burning or stinging to application site

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Warnings

Contraindications

Documented hypersensitivity to any ingredient

Cautions

Temporary burning or stinging may occur when first applied to broken skin

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Pregnancy & Lactation

Pregnancy

No data are available regarding use in pregnant women

Lactation

No data are available in breastfeeding women

The development and health benefits of breastfeeding should be considered along with the mother’s clinical need for the drug and any potential adverse effects on the breastfed child or from the underlying maternal condition

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

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Pharmacology

Mechanism of Action

Precise mechanism unknown; elicits moisturizing and antipruritic effects

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Administration

Topical Administration

Alevicyn Antimicrobial Dermal Spray: For irrigation only, not for injection

Alevicyn Antipruritic SG: For topical use only; shake well before each use

Storage

Store with cap closed tightly after each use in its original container

Store at 59-77F (15-25C) away from direct sunlight and heat sources

Do not allow to freeze

Use within 30 days of opening; discard remaining product after 30 days

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Formulary

FormularyPatient Discounts

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The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.