Bifidobacterium (OTC)

Brand and Other Names:Align, Bifidobacterium infantis

Suggested Dosing

Align: 1 capsule (4 mg) PO daily


Suggested Uses

Intestinal Flora Restoration

Restoration of intestinal flora, post-antibiotic diarrhea and prevention of post-antibiotic vulvovaginal candidiasis


Adverse Effects






Immunocompromised patients

GI wall perforation


If on a lactose-free diet, talk with healthcare practitioner; some products have lactose

If you have high blood sugar (diabetes), check labels closely; some products have sugar

Tell doctor if pregnant or planning on getting pregnant; discuss benefits and risks of using probiotic capsules while pregnant

Tell healthcare practitioner if breast-feeding; discuss possible risks to the baby

Inform healthcare practitioner about all drugs (prescription or OTC, natural products, vitamins) and health conditions; must check to make sure that it is safe to take probiotic capsules with all drugs and health conditions; do not start, stop, or change the dose of any drug without checking with healthcare practitioner

See healthcare professional or get medical help right away if experiencing any of the following signs or symptoms that may be related to a very bad side effect; signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat


Pregnancy & Lactation


Ask healthcare professional


Ask healthcare professional

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.



Mechanism of Action

Restores normal bowel flora that inhibit growth of harmful bacteria; stimulates local immunity; promotes water reabsorption in colon

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.