Suggested Dosing
General Dosing Guidelines
Pure comopound: 13-75 mg/day PO
Capsule: 10-30 mg BID PO
Prostate Cancer
15 mg BID PO
Oral Leukoplakia
4-8 mg/day PO
Specific lycopene supplement (LycoRed)
Preventing Exercise-induced Asthma
30 mg/day PO
Suggested Uses
Cancer, preventing atherosclerosis, cardiovascular disease, prostate cancer, HPV infection, cataracts, asthma, antioxidant, & anti-inflammatory
Efficacy
Bladder & colon cancer: There is no association between lycopene and the risk of cancer
Cardiovascular disease: Conflicting studies; more studies are needed to determine effectiveness
Atherosclerosis: Insufficient information
Oral leukoplakia: Preliminary evidence suggests significant clinical response
Ovarian, pancreatic prostate, & lung cancer: Evidence suggests it may reduce risk
HPV: Research suggests that women with higher levels of lycopene cleared oncogenic HPV in an average of 8.5 months compared to 11-12 months in women with lower levels
Adverse Effects
None reported
Warnings
Contraindications
None reported
Pregnancy & Lactation
Pregnancy Category: avoid use
Lactation: avoid use
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Metabolism: N/A
Excretion: N/A
Mechanism of Action
Antioxidant with particular affinity for prostate
