amoxicillin/omeprazole/rifabutin (Pending FDA Approval)

Brand and Other Names:Talicia
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Dosing & Uses

Helicobacter Pylori Infection

Pending FDA approved for treatment of Helicobacter pylori (H pylori) infection

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Interactions

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and amoxicillin/omeprazole/rifabutin

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            Pharmacology

            Mechanism of Action

            Amoxicillin: Ampicillin derivative; elicits antibacterial effect by inhibiting biosynthesis of cell wall mucopeptide

            Omeprazole: Proton pump inhibitor; binds to H+/K+-exchange ATPase (proton pump) in gastric parietal cells resulting in blocking acid secretion

            Rifabutin: Elicits antibacterial effects by inhibiting DNA-dependent RNA polymerase

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            Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.