Dosing & Uses
Dosage Forms & Strengths
lidocaine/hydrocortisone
topical pads
- 2%/2%
rectal gel
- 2%/2.5%
rectal cream
- 2%/2%
Skin Disorders
Apply q8-12hr
Hemorrhoids, Anal fissures, Pruritus ani
Apply BID to areas of discomfort and anal opening
Safety and efficacy not established
Adverse Effects
Frequency Not Defined
Adrenal suppression
Anaphylaxis
Angioedema
Blanching
Cushing syndrome
Stinging
Hirsutism
Acne
Cutaneous and subcutaneous atrophy
Dry scaly skin
Echymoses and petechia
Hyperpigmentation
Hypopigmentation
Edema
Urticaria
Impaired wound healing
Rash
Warnings
Contraindications
Hypersensitivity
Cautions
Systemic absorption of topical corticosteroids may cause hypothalamic-pituitary axis suppression when applied over large surface areas; other adverse effects include hyperglycemia, HPA suppression, glycosuria, fluid and electrolyte changes, hyperglycemia etc
Allergic contact dermatitis
Prolonged treatment with corticosteroids is associated with development of Kaposi’s sarcoma
Discontinue if infection develops.
Pregnancy & Lactation
Pregnancy Category: C
Lactation: Unknown if distributed in breast milk; exercise caution
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Combination therapy; anti-inflammatory, antipruritic, and vasoconstrictive effects
Absorption
Rectal absorption: 26%
Administration
Instructions
Insert applicator gently into anal area when administering
For external use only; avoid contact with eyes, nose, or ears
Images
| BRAND | FORM. | UNIT PRICE | PILL IMAGE |
|---|---|---|---|
| lidocaine-hydrocortisone topical - | 3-0.5 % cream |  | |
| lidocaine-hydrocortisone topical - | 3-0.5 % cream |  | |
| lidocaine-hydrocortisone topical - | 3-0.5 % cream |  | |
| lidocaine-hydrocortisone rectal - | 3 %-2.5 % (7 gram) gel |  | |
| lidocaine-hydrocortisone rectal - | 3-0.5 % kit |  | |
| lidocaine-hydrocortisone rectal - | 3-1 % (7 gram) kit |  | |
| lidocaine-hydrocortisone rectal - | 3-0.5 % cream |  |
Copyright © 2010 First DataBank, Inc.
Patient Handout
lidocaine-hydrocortisone topical
HYDROCORTISONE/LIDOCAINE - TOPICAL
(HYE-droe-KOR-ti-sone/LIE-doh-cane)
COMMON BRAND NAME(S): Lida Mantle HC
USES: This combination medication is used to treat irritation, soreness, and itchiness from certain skin conditions (such as scrapes, minor burns, eczema, insect bites). It can also be used to treat minor discomfort and itching caused by hemorrhoids and other problems of the anal area (such as anal fissures). This medication contains lidocaine, an anesthetic that works to decrease pain by temporarily numbing the area. This product also contains hydrocortisone, a corticosteroid that reduces redness, itching, and swelling.
HOW TO USE: Wash your hands before applying the medication. Clean and dry the area to be treated.Apply a thin layer of medication to the affected area of skin as directed by your doctor, usually 2 or 3 times daily. If you are using the medicated pads, use each pad only once and discard the pad after one use. Do not save used pads for later.To apply this medication to the outside of the anus, apply a small amount to the affected area and rub in gently. Do not apply this medication inside the anus.The dosage is based on your medical condition and response to treatment. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same times each day.Do not use on large areas of the body, apply heat or cover the area with waterproof bandages or plastic unless directed to do so by your doctor.Wash hands immediately after use unless you are treating an area on the hands. Avoid getting the product in your eyes, nose, ears, or mouth. If the medication gets in these areas, rinse the area immediately with clean water.Do not use more of this product, use it more often, or keep using it longer than prescribed by your doctor. If you have been using this medication for a long time or in high doses, do not suddenly stop using it without your doctor's approval. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.Inform your doctor if your condition does not improve or if it worsens after 1 to 2 weeks.
SIDE EFFECTS: Redness, swelling, or temporary numbness at the treated area may occur. If any of these effects last or get worse, tell your doctor.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: change in skin appearance (such as color, stretch marks, thinning skin), skin redness/tenderness/pus or other signs of infection.Get medical help right away if you have any very serious side effects, including: slow/shallow breathing, signs of serious infection (such as sore throat that doesn't go away, fever), seizures, pale/bluish/gray skin, unusual tiredness, shortness of breath, fast/slow/irregular heartbeat.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice any other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Before using this product, tell your doctor or pharmacist if you are allergic to lidocaine; or to other amide anesthetics (such as bupivacaine, prilocaine); or to hydrocortisone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, eye problems, current/recent infections (such as tuberculosis, chickenpox, herpes), skin sores/infections (such as fungal infections), liver disease, stomach/intestinal problems, a certain blood disorder (methemoglobinemia).If there is an infection or sore in the area to be treated, do not use this medication without consulting your doctor first.Children may be more sensitive to the effects of too much corticosteroid medication. Consult your doctor for more details.During pregnancy, this medication should be used only when clearly needed. It should not be used for long periods of time or in large amounts. Discuss the risks and benefits with your doctor.Lidocaine passes into breast milk. It is unknown if hydrocortisone passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
OVERDOSE: This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
NOTES: This medication has been prescribed for your current condition only. Do not use it later for another condition unless told to do so by your doctor. A different medication may be necessary in that case.
MISSED DOSE: If you miss a dose, use it as soon as you remember unless it is almost time for the next dose. In that case, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.
STORAGE: Store at room temperature. Do not refrigerate. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised April 2023. Copyright(c) 2023 First Databank, Inc.
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
Formulary
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