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      Drugs & Diseases

      American Ginseng (Herb/Suppl)

      Brand and Other Names:Anchi Ginseng, Canadian Ginseng, more...North American Ginseng, Ontario Ginseng, Panax Quinquefolius, Red Berry, Sang, Wisconsin Ginseng
      • Print

      Suggested Dosing

      Younger

      0.25-0.5 g dried root PO BID x 15-20 d, then 2 weeks off

      ADHD: combination product (AD-fx; 200mg American Ginseng/ 50 mg gingko) PO BID x4 week

      Geriatric

      0.4-0.8 g dried root PO qD continuously

      Diabetes Mellitus

      3-9 g 2hr before meal (no added benefit of >3 g)

      Respiratory Infections

      200 mg PO BID x 3-4mos (Cold-FX)

      Next:

      Suggested Uses

      Adaptogen: adapt to internal/external stressors, fight fatigue, increased stamina

      Anemia, athletic performance enhancement, diabetes, digestion problems, gastritis, immunostimulant, impotence, infection, stress

      Efficacy

      Possibly effective for diabetes and respiratory tract infections

      Insufficient reliable information for other uses

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      Next:

      Interactions

      Interaction Checker

      and American Ginseng

      No Results

         activity indicator 
        No Interactions Found
        Interactions Found

        Contraindicated

          Serious - Use Alternative

            Significant - Monitor Closely

              Minor

                All Interactions Sort By:
                 activity indicator 

                Contraindicated (0)

                  Serious - Use Alternative (0)

                    Monitor Closely (68)

                    • aceclofenac

                      aceclofenac and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • acemetacin

                      acemetacin and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • agrimony

                      agrimony and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • alfalfa

                      alfalfa and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • alteplase

                      alteplase and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • antithrombin alfa

                      antithrombin alfa and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • antithrombin III

                      antithrombin III and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • argatroban

                      argatroban and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • aspirin

                      aspirin and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • aspirin rectal

                      aspirin rectal and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • aspirin/citric acid/sodium bicarbonate

                      aspirin/citric acid/sodium bicarbonate and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • bemiparin

                      bemiparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • bivalirudin

                      bivalirudin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • celecoxib

                      celecoxib and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • choline magnesium trisalicylate

                      choline magnesium trisalicylate and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • cinnamon

                      American ginseng and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • cordyceps

                      American ginseng and cordyceps both increase anticoagulation. Use Caution/Monitor.

                    • dabigatran

                      dabigatran and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • dalteparin

                      dalteparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • diclofenac

                      diclofenac and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • diflunisal

                      diflunisal and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • dong quai

                      American ginseng and dong quai both increase anticoagulation. Use Caution/Monitor.

                    • enoxaparin

                      enoxaparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • epoprostenol

                      American ginseng and epoprostenol both increase anticoagulation. Use Caution/Monitor.

                    • etodolac

                      etodolac and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • fennel

                      American ginseng and fennel both increase anticoagulation. Use Caution/Monitor.

                    • fenoprofen

                      fenoprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • feverfew

                      American ginseng and feverfew both increase anticoagulation. Use Caution/Monitor.

                    • flurbiprofen

                      flurbiprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • fondaparinux

                      fondaparinux and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • forskolin

                      American ginseng and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • garlic

                      American ginseng and garlic both increase anticoagulation. Use Caution/Monitor.

                    • ginger

                      American ginseng and ginger both increase anticoagulation. Use Caution/Monitor.

                    • ginkgo biloba

                      American ginseng and ginkgo biloba both increase anticoagulation. Use Caution/Monitor.

                    • heparin

                      heparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • horse chestnut seed

                      American ginseng and horse chestnut seed both increase anticoagulation. Use Caution/Monitor.

                    • ibuprofen

                      ibuprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • ibuprofen IV

                      ibuprofen IV and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • indomethacin

                      indomethacin and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • ketoprofen

                      ketoprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • ketorolac

                      ketorolac and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • ketorolac intranasal

                      ketorolac intranasal and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • lornoxicam

                      lornoxicam and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • meclofenamate

                      meclofenamate and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • mefenamic acid

                      mefenamic acid and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • meloxicam

                      meloxicam and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • mistletoe

                      American ginseng increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                    • nabumetone

                      nabumetone and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • naproxen

                      naproxen and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • nettle

                      American ginseng increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                    • oxaprozin

                      oxaprozin and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • panax ginseng

                      American ginseng and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                    • parecoxib

                      parecoxib and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • pau d'arco

                      American ginseng and pau d'arco both increase anticoagulation. Use Caution/Monitor.

                    • phenindione

                      phenindione and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • phytoestrogens

                      American ginseng and phytoestrogens both increase anticoagulation. Use Caution/Monitor.

                    • piroxicam

                      piroxicam and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • protamine

                      protamine and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • reishi

                      American ginseng and reishi both increase anticoagulation. Use Caution/Monitor.

                    • reteplase

                      reteplase and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • salicylates (non-asa)

                      salicylates (non-asa) and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • salsalate

                      salsalate and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • Siberian ginseng

                      American ginseng and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.

                    • sulfasalazine

                      sulfasalazine and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • sulindac

                      sulindac and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • tenecteplase

                      tenecteplase and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • tolfenamic acid

                      tolfenamic acid and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    • tolmetin

                      tolmetin and American ginseng both increase anticoagulation. Use Caution/Monitor.

                    Minor (39)

                    • acarbose

                      American ginseng increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown.

                    • anamu

                      American ginseng and anamu both increase anticoagulation. Minor/Significance Unknown.

                    • armodafinil

                      American ginseng increases effects of armodafinil by pharmacodynamic synergism. Minor/Significance Unknown.

                    • caffeine

                      American ginseng increases effects of caffeine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • chlorpropamide

                      American ginseng increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • danshen

                      American ginseng and danshen both increase anticoagulation. Minor/Significance Unknown.

                    • devil's claw

                      American ginseng and devil's claw both increase anticoagulation. Minor/Significance Unknown.

                    • dexmethylphenidate

                      American ginseng increases effects of dexmethylphenidate by pharmacodynamic synergism. Minor/Significance Unknown.

                    • dextroamphetamine

                      American ginseng increases effects of dextroamphetamine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • glimepiride

                      American ginseng increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown.

                    • glipizide

                      American ginseng increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • glyburide

                      American ginseng increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • green tea

                      green tea, American ginseng. Other (see comment). Minor/Significance Unknown. Comment: Use caution when combining green tea with herbs that exhibit antiplatelet effects or anticoagulant activity.

                    • insulin aspart

                      American ginseng increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown.

                    • insulin detemir

                      American ginseng increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown.

                    • insulin glargine

                      American ginseng increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • insulin glulisine

                      American ginseng increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • insulin lispro

                      American ginseng increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown.

                    • insulin NPH

                      American ginseng increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown.

                    • insulin regular human

                      American ginseng increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown.

                    • lisdexamfetamine

                      American ginseng increases effects of lisdexamfetamine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • metformin

                      American ginseng increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown.

                    • methamphetamine

                      American ginseng increases effects of methamphetamine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • methylenedioxymethamphetamine

                      American ginseng increases effects of methylenedioxymethamphetamine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • methylphenidate

                      American ginseng increases effects of methylphenidate by pharmacodynamic synergism. Minor/Significance Unknown.

                    • miglitol

                      American ginseng increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • modafinil

                      American ginseng increases effects of modafinil by pharmacodynamic synergism. Minor/Significance Unknown.

                    • nateglinide

                      American ginseng increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • phentermine

                      American ginseng increases effects of phentermine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • pioglitazone

                      American ginseng increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown.

                    • repaglinide

                      American ginseng increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • rosiglitazone

                      American ginseng increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown.

                    • saxagliptin

                      American ginseng increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                    • serdexmethylphenidate/dexmethylphenidate

                      American ginseng increases effects of serdexmethylphenidate/dexmethylphenidate by pharmacodynamic synergism. Minor/Significance Unknown.

                    • sitagliptin

                      American ginseng increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                    • tolazamide

                      American ginseng increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • tolbutamide

                      American ginseng increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • vildagliptin

                      American ginseng increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                    • yohimbine

                      American ginseng increases effects of yohimbine by pharmacodynamic synergism. Minor/Significance Unknown.

                    Previous
                    Next:

                    Adverse Effects

                    Frequency Not Defined

                    Allergic skin reactions

                    Diarrhea

                    Headache

                    HTN

                    Insomnia

                    Itching

                    Increased libido

                    Nervousness

                    Palpitations

                    Vaginal bleeding

                    Previous
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                    Warnings

                    Contraindications

                    Hypertension, pregnancy

                    Breast CA, endometrial CA, endometriosis, hemorrhage, hormone sensitive conditions, ovarian CA, thrombosis, uterine fibroids

                    Avoid prior to surgery: may cause bleeding

                    Cautions

                    Bleeding disorders, cardiac disorders, diabetes mellitus, hypotension, insomnia, schizophrenia

                    Previous
                    Next:

                    Pregnancy & Lactation

                    Pregnancy Category: N/A

                    Lactation: N/A

                    Pregnancy Categories

                    A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                    B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                    C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                    D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                    X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                    NA: Information not available.

                    Previous
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                    Pharmacology

                    Mechanism of Action

                    Ginsenosides have various metabolic effects

                    Metabolism: N/A

                    Excretion: N/A

                    Previous
                    Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
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