American Ginseng (Herb/Suppl)

Brand and Other Names:Anchi Ginseng, Canadian Ginseng, more...North American Ginseng, Ontario Ginseng, Panax Quinquefolius, Red Berry, Sang, Wisconsin Ginseng
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Suggested Dosing

Younger

0.25-0.5 g dried root PO BID x 15-20 d, then 2 weeks off

ADHD: combination product (AD-fx; 200mg American Ginseng/ 50 mg gingko) PO BID x4 week

Geriatric

0.4-0.8 g dried root PO qD continuously

Diabetes Mellitus

3-9 g 2hr before meal (no added benefit of >3 g)

Respiratory Infections

200 mg PO BID x 3-4mos (Cold-FX)

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Suggested Uses

Adaptogen: adapt to internal/external stressors, fight fatigue, increased stamina

Anemia, athletic performance enhancement, diabetes, digestion problems, gastritis, immunostimulant, impotence, infection, stress

Efficacy

Possibly effective for diabetes and respiratory tract infections

Insufficient reliable information for other uses

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Interactions

Interaction Checker

and American Ginseng

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

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             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (69)

                • aceclofenac

                  aceclofenac and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • acemetacin

                  acemetacin and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • agrimony

                  agrimony and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • alfalfa

                  alfalfa and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • alteplase

                  alteplase and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • antithrombin alfa

                  antithrombin alfa and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • antithrombin III

                  antithrombin III and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • argatroban

                  argatroban and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • aspirin

                  aspirin and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • aspirin rectal

                  aspirin rectal and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • aspirin/citric acid/sodium bicarbonate

                  aspirin/citric acid/sodium bicarbonate and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • bemiparin

                  bemiparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • bivalirudin

                  bivalirudin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • celecoxib

                  celecoxib and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • choline magnesium trisalicylate

                  choline magnesium trisalicylate and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • cinnamon

                  American ginseng and cinnamon both increase anticoagulation. Use Caution/Monitor.

                • cordyceps

                  American ginseng and cordyceps both increase anticoagulation. Use Caution/Monitor.

                • dabigatran

                  dabigatran and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • dalteparin

                  dalteparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • diclofenac

                  diclofenac and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • diflunisal

                  diflunisal and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • dong quai

                  American ginseng and dong quai both increase anticoagulation. Use Caution/Monitor.

                • enoxaparin

                  enoxaparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • epoprostenol

                  American ginseng and epoprostenol both increase anticoagulation. Use Caution/Monitor.

                • etodolac

                  etodolac and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • fennel

                  American ginseng and fennel both increase anticoagulation. Use Caution/Monitor.

                • fenoprofen

                  fenoprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • feverfew

                  American ginseng and feverfew both increase anticoagulation. Use Caution/Monitor.

                • flurbiprofen

                  flurbiprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • fondaparinux

                  fondaparinux and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • forskolin

                  American ginseng and forskolin both increase anticoagulation. Use Caution/Monitor.

                • garlic

                  American ginseng and garlic both increase anticoagulation. Use Caution/Monitor.

                • ginger

                  American ginseng and ginger both increase anticoagulation. Use Caution/Monitor.

                • ginkgo biloba

                  American ginseng and ginkgo biloba both increase anticoagulation. Use Caution/Monitor.

                • heparin

                  heparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • horse chestnut seed

                  American ginseng and horse chestnut seed both increase anticoagulation. Use Caution/Monitor.

                • ibuprofen

                  ibuprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • ibuprofen IV

                  ibuprofen IV and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • indomethacin

                  indomethacin and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • ketoprofen

                  ketoprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • ketorolac

                  ketorolac and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • ketorolac intranasal

                  ketorolac intranasal and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • lornoxicam

                  lornoxicam and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • meclofenamate

                  meclofenamate and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • mefenamic acid

                  mefenamic acid and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • meloxicam

                  meloxicam and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • mistletoe

                  American ginseng increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • nabumetone

                  nabumetone and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • naproxen

                  naproxen and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • nettle

                  American ginseng increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • oxaprozin

                  oxaprozin and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • panax ginseng

                  American ginseng and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • parecoxib

                  parecoxib and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • pau d'arco

                  American ginseng and pau d'arco both increase anticoagulation. Use Caution/Monitor.

                • phenindione

                  phenindione and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • phytoestrogens

                  American ginseng and phytoestrogens both increase anticoagulation. Use Caution/Monitor.

                • piroxicam

                  piroxicam and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • protamine

                  protamine and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • reishi

                  American ginseng and reishi both increase anticoagulation. Use Caution/Monitor.

                • reteplase

                  reteplase and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • salicylates (non-asa)

                  salicylates (non-asa) and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • salsalate

                  salsalate and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • Siberian ginseng

                  American ginseng and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.

                • sulfasalazine

                  sulfasalazine and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • sulindac

                  sulindac and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • tenecteplase

                  tenecteplase and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                • tolfenamic acid

                  tolfenamic acid and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • tolmetin

                  tolmetin and American ginseng both increase anticoagulation. Use Caution/Monitor.

                • warfarin

                  warfarin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.

                Minor (38)

                • acarbose

                  American ginseng increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown.

                • anamu

                  American ginseng and anamu both increase anticoagulation. Minor/Significance Unknown.

                • armodafinil

                  American ginseng increases effects of armodafinil by pharmacodynamic synergism. Minor/Significance Unknown.

                • caffeine

                  American ginseng increases effects of caffeine by pharmacodynamic synergism. Minor/Significance Unknown.

                • chlorpropamide

                  American ginseng increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown.

                • danshen

                  American ginseng and danshen both increase anticoagulation. Minor/Significance Unknown.

                • devil's claw

                  American ginseng and devil's claw both increase anticoagulation. Minor/Significance Unknown.

                • dexmethylphenidate

                  American ginseng increases effects of dexmethylphenidate by pharmacodynamic synergism. Minor/Significance Unknown.

                • dextroamphetamine

                  American ginseng increases effects of dextroamphetamine by pharmacodynamic synergism. Minor/Significance Unknown.

                • glimepiride

                  American ginseng increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown.

                • glipizide

                  American ginseng increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown.

                • glyburide

                  American ginseng increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown.

                • green tea

                  green tea, American ginseng. Other (see comment). Minor/Significance Unknown. Comment: Use caution when combining green tea with herbs that exhibit antiplatelet effects or anticoagulant activity.

                • insulin aspart

                  American ginseng increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin detemir

                  American ginseng increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin glargine

                  American ginseng increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin glulisine

                  American ginseng increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin lispro

                  American ginseng increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin NPH

                  American ginseng increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin regular human

                  American ginseng increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown.

                • lisdexamfetamine

                  American ginseng increases effects of lisdexamfetamine by pharmacodynamic synergism. Minor/Significance Unknown.

                • metformin

                  American ginseng increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown.

                • methamphetamine

                  American ginseng increases effects of methamphetamine by pharmacodynamic synergism. Minor/Significance Unknown.

                • methylenedioxymethamphetamine

                  American ginseng increases effects of methylenedioxymethamphetamine by pharmacodynamic synergism. Minor/Significance Unknown.

                • methylphenidate

                  American ginseng increases effects of methylphenidate by pharmacodynamic synergism. Minor/Significance Unknown.

                • miglitol

                  American ginseng increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown.

                • modafinil

                  American ginseng increases effects of modafinil by pharmacodynamic synergism. Minor/Significance Unknown.

                • nateglinide

                  American ginseng increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown.

                • phentermine

                  American ginseng increases effects of phentermine by pharmacodynamic synergism. Minor/Significance Unknown.

                • pioglitazone

                  American ginseng increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown.

                • repaglinide

                  American ginseng increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown.

                • rosiglitazone

                  American ginseng increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown.

                • saxagliptin

                  American ginseng increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                • sitagliptin

                  American ginseng increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                • tolazamide

                  American ginseng increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown.

                • tolbutamide

                  American ginseng increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown.

                • vildagliptin

                  American ginseng increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                • yohimbine

                  American ginseng increases effects of yohimbine by pharmacodynamic synergism. Minor/Significance Unknown.

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                Adverse Effects

                Frequency Not Defined

                Allergic skin reactions

                Diarrhea

                Headache

                HTN

                Insomnia

                Itching

                Increased libido

                Nervousness

                Palpitations

                Vaginal bleeding

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                Warnings

                Contraindications

                Hypertension, pregnancy

                Breast CA, endometrial CA, endometriosis, hemorrhage, hormone sensitive conditions, ovarian CA, thrombosis, uterine fibroids

                Avoid prior to surgery: may cause bleeding

                Cautions

                Bleeding disorders, cardiac disorders, diabetes mellitus, hypotension, insomnia, schizophrenia

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                Pregnancy & Lactation

                Pregnancy Category: N/A

                Lactation: N/A

                Pregnancy Categories

                A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                NA: Information not available.

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                Pharmacology

                Mechanism of Action

                Ginsenosides have various metabolic effects

                Metabolism: N/A

                Excretion: N/A

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                Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.