Indication-specific dosing for Anchi Ginseng, Canadian Ginseng, North American Ginseng American ginseng in combination, frequency-based adverse effects, comprehensive interactions, contraindications ... and more

Sections

Sections American Ginseng
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Suggested Dosing

Younger

0.25-0.5 g dried root PO BID x 15-20 d, then 2 weeks off

ADHD: combination product (AD-fx; 200mg American Ginseng/ 50 mg gingko) PO BID x4 week

Geriatric

0.4-0.8 g dried root PO qD continuously

Diabetes Mellitus

3-9 g 2hr before meal (no added benefit of >3 g)

Respiratory Infections

200 mg PO BID x 3-4mos (Cold-FX)

Suggested Uses

Adaptogen: adapt to internal/external stressors, fight fatigue, increased stamina

Anemia, athletic performance enhancement, diabetes, digestion problems, gastritis, immunostimulant, impotence, infection, stress

Efficacy

Possibly effective for diabetes and respiratory tract infections

Insufficient reliable information for other uses

Interaction Checker

Enter a drug name and American Ginseng

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Contraindicated

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Minor

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Contraindicated (0)

Serious - Use Alternative (0)

Monitor Closely (68)

aceclofenac
aceclofenac and American ginseng both increase anticoagulation. Use Caution/Monitor.
acemetacin
acemetacin and American ginseng both increase anticoagulation. Use Caution/Monitor.
agrimony
agrimony and American ginseng both increase anticoagulation. Use Caution/Monitor.
alfalfa
alfalfa and American ginseng both increase anticoagulation. Use Caution/Monitor.
alteplase
alteplase and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
antithrombin alfa
antithrombin alfa and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
antithrombin III
antithrombin III and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
argatroban
argatroban and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
aspirin
aspirin and American ginseng both increase anticoagulation. Use Caution/Monitor.
aspirin rectal
aspirin rectal and American ginseng both increase anticoagulation. Use Caution/Monitor.
aspirin/citric acid/sodium bicarbonate
aspirin/citric acid/sodium bicarbonate and American ginseng both increase anticoagulation. Use Caution/Monitor.
bemiparin
bemiparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
bivalirudin
bivalirudin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
celecoxib
celecoxib and American ginseng both increase anticoagulation. Use Caution/Monitor.
choline magnesium trisalicylate
choline magnesium trisalicylate and American ginseng both increase anticoagulation. Use Caution/Monitor.
cinnamon
American ginseng and cinnamon both increase anticoagulation. Use Caution/Monitor.
cordyceps
American ginseng and cordyceps both increase anticoagulation. Use Caution/Monitor.
dabigatran
dabigatran and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
dalteparin
dalteparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
diclofenac
diclofenac and American ginseng both increase anticoagulation. Use Caution/Monitor.
diflunisal
diflunisal and American ginseng both increase anticoagulation. Use Caution/Monitor.
dong quai
American ginseng and dong quai both increase anticoagulation. Use Caution/Monitor.
enoxaparin
enoxaparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
epoprostenol
American ginseng and epoprostenol both increase anticoagulation. Use Caution/Monitor.
etodolac
etodolac and American ginseng both increase anticoagulation. Use Caution/Monitor.
fennel
American ginseng and fennel both increase anticoagulation. Use Caution/Monitor.
fenoprofen
fenoprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.
feverfew
American ginseng and feverfew both increase anticoagulation. Use Caution/Monitor.
flurbiprofen
flurbiprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.
fondaparinux
fondaparinux and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
forskolin
American ginseng and forskolin both increase anticoagulation. Use Caution/Monitor.
garlic
American ginseng and garlic both increase anticoagulation. Use Caution/Monitor.
ginger
American ginseng and ginger both increase anticoagulation. Use Caution/Monitor.
ginkgo biloba
American ginseng and ginkgo biloba both increase anticoagulation. Use Caution/Monitor.
heparin
heparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
horse chestnut seed
American ginseng and horse chestnut seed both increase anticoagulation. Use Caution/Monitor.
ibuprofen
ibuprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.
ibuprofen IV
ibuprofen IV and American ginseng both increase anticoagulation. Use Caution/Monitor.
indomethacin
indomethacin and American ginseng both increase anticoagulation. Use Caution/Monitor.
ketoprofen
ketoprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.
ketorolac
ketorolac and American ginseng both increase anticoagulation. Use Caution/Monitor.
ketorolac intranasal
ketorolac intranasal and American ginseng both increase anticoagulation. Use Caution/Monitor.
lornoxicam
lornoxicam and American ginseng both increase anticoagulation. Use Caution/Monitor.
meclofenamate
meclofenamate and American ginseng both increase anticoagulation. Use Caution/Monitor.
mefenamic acid
mefenamic acid and American ginseng both increase anticoagulation. Use Caution/Monitor.
meloxicam
meloxicam and American ginseng both increase anticoagulation. Use Caution/Monitor.
mistletoe
American ginseng increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
nabumetone
nabumetone and American ginseng both increase anticoagulation. Use Caution/Monitor.
naproxen
naproxen and American ginseng both increase anticoagulation. Use Caution/Monitor.
nettle
American ginseng increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
oxaprozin
oxaprozin and American ginseng both increase anticoagulation. Use Caution/Monitor.
panax ginseng
American ginseng and panax ginseng both increase anticoagulation. Use Caution/Monitor.
parecoxib
parecoxib and American ginseng both increase anticoagulation. Use Caution/Monitor.
pau d'arco
American ginseng and pau d'arco both increase anticoagulation. Use Caution/Monitor.
phenindione
phenindione and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
phytoestrogens
American ginseng and phytoestrogens both increase anticoagulation. Use Caution/Monitor.
piroxicam
piroxicam and American ginseng both increase anticoagulation. Use Caution/Monitor.
protamine
protamine and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
reishi
American ginseng and reishi both increase anticoagulation. Use Caution/Monitor.
reteplase
reteplase and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
salicylates (non-asa)
salicylates (non-asa) and American ginseng both increase anticoagulation. Use Caution/Monitor.
salsalate
salsalate and American ginseng both increase anticoagulation. Use Caution/Monitor.
Siberian ginseng
American ginseng and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.
sulfasalazine
sulfasalazine and American ginseng both increase anticoagulation. Use Caution/Monitor.
sulindac
sulindac and American ginseng both increase anticoagulation. Use Caution/Monitor.
tenecteplase
tenecteplase and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
tolfenamic acid
tolfenamic acid and American ginseng both increase anticoagulation. Use Caution/Monitor.
tolmetin
tolmetin and American ginseng both increase anticoagulation. Use Caution/Monitor.

Minor (39)

acarbose
American ginseng increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown.
anamu
American ginseng and anamu both increase anticoagulation. Minor/Significance Unknown.
armodafinil
American ginseng increases effects of armodafinil by pharmacodynamic synergism. Minor/Significance Unknown.
caffeine
American ginseng increases effects of caffeine by pharmacodynamic synergism. Minor/Significance Unknown.
chlorpropamide
American ginseng increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown.
danshen
American ginseng and danshen both increase anticoagulation. Minor/Significance Unknown.
devil's claw
American ginseng and devil's claw both increase anticoagulation. Minor/Significance Unknown.
dexmethylphenidate
American ginseng increases effects of dexmethylphenidate by pharmacodynamic synergism. Minor/Significance Unknown.
dextroamphetamine
American ginseng increases effects of dextroamphetamine by pharmacodynamic synergism. Minor/Significance Unknown.
glimepiride
American ginseng increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown.
glipizide
American ginseng increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown.
glyburide
American ginseng increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown.
green tea
green tea, American ginseng. Other (see comment). Minor/Significance Unknown. Comment: Use caution when combining green tea with herbs that exhibit antiplatelet effects or anticoagulant activity.
insulin aspart
American ginseng increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown.
insulin detemir
American ginseng increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown.
insulin glargine
American ginseng increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown.
insulin glulisine
American ginseng increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown.
insulin lispro
American ginseng increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown.
insulin NPH
American ginseng increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown.
insulin regular human
American ginseng increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown.
lisdexamfetamine
American ginseng increases effects of lisdexamfetamine by pharmacodynamic synergism. Minor/Significance Unknown.
metformin
American ginseng increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown.
methamphetamine
American ginseng increases effects of methamphetamine by pharmacodynamic synergism. Minor/Significance Unknown.
methylenedioxymethamphetamine
American ginseng increases effects of methylenedioxymethamphetamine by pharmacodynamic synergism. Minor/Significance Unknown.
methylphenidate
American ginseng increases effects of methylphenidate by pharmacodynamic synergism. Minor/Significance Unknown.
miglitol
American ginseng increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown.
modafinil
American ginseng increases effects of modafinil by pharmacodynamic synergism. Minor/Significance Unknown.
nateglinide
American ginseng increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown.
phentermine
American ginseng increases effects of phentermine by pharmacodynamic synergism. Minor/Significance Unknown.
pioglitazone
American ginseng increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown.
repaglinide
American ginseng increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown.
rosiglitazone
American ginseng increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown.
saxagliptin
American ginseng increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown.
serdexmethylphenidate/dexmethylphenidate
American ginseng increases effects of serdexmethylphenidate/dexmethylphenidate by pharmacodynamic synergism. Minor/Significance Unknown.
sitagliptin
American ginseng increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown.
tolazamide
American ginseng increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown.
tolbutamide
American ginseng increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown.
vildagliptin
American ginseng increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown.
yohimbine
American ginseng increases effects of yohimbine by pharmacodynamic synergism. Minor/Significance Unknown.

acarbose
Minor (1)American ginseng increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown.
aceclofenac
Monitor Closely (1)aceclofenac and American ginseng both increase anticoagulation. Use Caution/Monitor.
acemetacin
Monitor Closely (1)acemetacin and American ginseng both increase anticoagulation. Use Caution/Monitor.
agrimony
Monitor Closely (1)agrimony and American ginseng both increase anticoagulation. Use Caution/Monitor.
alfalfa
Monitor Closely (1)alfalfa and American ginseng both increase anticoagulation. Use Caution/Monitor.
alteplase
Monitor Closely (1)alteplase and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
anamu
Minor (1)American ginseng and anamu both increase anticoagulation. Minor/Significance Unknown.
antithrombin alfa
Monitor Closely (1)antithrombin alfa and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
antithrombin III
Monitor Closely (1)antithrombin III and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
argatroban
Monitor Closely (1)argatroban and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
armodafinil
Minor (1)American ginseng increases effects of armodafinil by pharmacodynamic synergism. Minor/Significance Unknown.
aspirin
Monitor Closely (1)aspirin and American ginseng both increase anticoagulation. Use Caution/Monitor.
aspirin rectal
Monitor Closely (1)aspirin rectal and American ginseng both increase anticoagulation. Use Caution/Monitor.
aspirin/citric acid/sodium bicarbonate
Monitor Closely (1)aspirin/citric acid/sodium bicarbonate and American ginseng both increase anticoagulation. Use Caution/Monitor.
bemiparin
Monitor Closely (1)bemiparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
bivalirudin
Monitor Closely (1)bivalirudin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
caffeine
Minor (1)American ginseng increases effects of caffeine by pharmacodynamic synergism. Minor/Significance Unknown.
celecoxib
Monitor Closely (1)celecoxib and American ginseng both increase anticoagulation. Use Caution/Monitor.
chlorpropamide
Minor (1)American ginseng increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown.
choline magnesium trisalicylate
Monitor Closely (1)choline magnesium trisalicylate and American ginseng both increase anticoagulation. Use Caution/Monitor.
cinnamon
Monitor Closely (1)American ginseng and cinnamon both increase anticoagulation. Use Caution/Monitor.
cordyceps
Monitor Closely (1)American ginseng and cordyceps both increase anticoagulation. Use Caution/Monitor.
dabigatran
Monitor Closely (1)dabigatran and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
dalteparin
Monitor Closely (1)dalteparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
danshen
Minor (1)American ginseng and danshen both increase anticoagulation. Minor/Significance Unknown.
devil's claw
Minor (1)American ginseng and devil's claw both increase anticoagulation. Minor/Significance Unknown.
dexmethylphenidate
Minor (1)American ginseng increases effects of dexmethylphenidate by pharmacodynamic synergism. Minor/Significance Unknown.
dextroamphetamine
Minor (1)American ginseng increases effects of dextroamphetamine by pharmacodynamic synergism. Minor/Significance Unknown.
diclofenac
Monitor Closely (1)diclofenac and American ginseng both increase anticoagulation. Use Caution/Monitor.
diflunisal
Monitor Closely (1)diflunisal and American ginseng both increase anticoagulation. Use Caution/Monitor.
dong quai
Monitor Closely (1)American ginseng and dong quai both increase anticoagulation. Use Caution/Monitor.
enoxaparin
Monitor Closely (1)enoxaparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
epoprostenol
Monitor Closely (1)American ginseng and epoprostenol both increase anticoagulation. Use Caution/Monitor.
etodolac
Monitor Closely (1)etodolac and American ginseng both increase anticoagulation. Use Caution/Monitor.
fennel
Monitor Closely (1)American ginseng and fennel both increase anticoagulation. Use Caution/Monitor.
fenoprofen
Monitor Closely (1)fenoprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.
feverfew
Monitor Closely (1)American ginseng and feverfew both increase anticoagulation. Use Caution/Monitor.
flurbiprofen
Monitor Closely (1)flurbiprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.
fondaparinux
Monitor Closely (1)fondaparinux and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
forskolin
Monitor Closely (1)American ginseng and forskolin both increase anticoagulation. Use Caution/Monitor.
garlic
Monitor Closely (1)American ginseng and garlic both increase anticoagulation. Use Caution/Monitor.
ginger
Monitor Closely (1)American ginseng and ginger both increase anticoagulation. Use Caution/Monitor.
ginkgo biloba
Monitor Closely (1)American ginseng and ginkgo biloba both increase anticoagulation. Use Caution/Monitor.
glimepiride
Minor (1)American ginseng increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown.
glipizide
Minor (1)American ginseng increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown.
glyburide
Minor (1)American ginseng increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown.
green tea
Minor (1)green tea, American ginseng. Other (see comment). Minor/Significance Unknown. Comment: Use caution when combining green tea with herbs that exhibit antiplatelet effects or anticoagulant activity.
heparin
Monitor Closely (1)heparin and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
horse chestnut seed
Monitor Closely (1)American ginseng and horse chestnut seed both increase anticoagulation. Use Caution/Monitor.
ibuprofen
Monitor Closely (1)ibuprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.
ibuprofen IV
Monitor Closely (1)ibuprofen IV and American ginseng both increase anticoagulation. Use Caution/Monitor.
indomethacin
Monitor Closely (1)indomethacin and American ginseng both increase anticoagulation. Use Caution/Monitor.
insulin aspart
Minor (1)American ginseng increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown.
insulin detemir
Minor (1)American ginseng increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown.
insulin glargine
Minor (1)American ginseng increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown.
insulin glulisine
Minor (1)American ginseng increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown.
insulin lispro
Minor (1)American ginseng increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown.
insulin NPH
Minor (1)American ginseng increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown.
insulin regular human
Minor (1)American ginseng increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown.
ketoprofen
Monitor Closely (1)ketoprofen and American ginseng both increase anticoagulation. Use Caution/Monitor.
ketorolac
Monitor Closely (1)ketorolac and American ginseng both increase anticoagulation. Use Caution/Monitor.
ketorolac intranasal
Monitor Closely (1)ketorolac intranasal and American ginseng both increase anticoagulation. Use Caution/Monitor.
lisdexamfetamine
Minor (1)American ginseng increases effects of lisdexamfetamine by pharmacodynamic synergism. Minor/Significance Unknown.
lornoxicam
Monitor Closely (1)lornoxicam and American ginseng both increase anticoagulation. Use Caution/Monitor.
meclofenamate
Monitor Closely (1)meclofenamate and American ginseng both increase anticoagulation. Use Caution/Monitor.
mefenamic acid
Monitor Closely (1)mefenamic acid and American ginseng both increase anticoagulation. Use Caution/Monitor.
meloxicam
Monitor Closely (1)meloxicam and American ginseng both increase anticoagulation. Use Caution/Monitor.
metformin
Minor (1)American ginseng increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown.
methamphetamine
Minor (1)American ginseng increases effects of methamphetamine by pharmacodynamic synergism. Minor/Significance Unknown.
methylenedioxymethamphetamine
Minor (1)American ginseng increases effects of methylenedioxymethamphetamine by pharmacodynamic synergism. Minor/Significance Unknown.
methylphenidate
Minor (1)American ginseng increases effects of methylphenidate by pharmacodynamic synergism. Minor/Significance Unknown.
miglitol
Minor (1)American ginseng increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown.
mistletoe
Monitor Closely (1)American ginseng increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
modafinil
Minor (1)American ginseng increases effects of modafinil by pharmacodynamic synergism. Minor/Significance Unknown.
nabumetone
Monitor Closely (1)nabumetone and American ginseng both increase anticoagulation. Use Caution/Monitor.
naproxen
Monitor Closely (1)naproxen and American ginseng both increase anticoagulation. Use Caution/Monitor.
nateglinide
Minor (1)American ginseng increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown.
nettle
Monitor Closely (1)American ginseng increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
oxaprozin
Monitor Closely (1)oxaprozin and American ginseng both increase anticoagulation. Use Caution/Monitor.
panax ginseng
Monitor Closely (1)American ginseng and panax ginseng both increase anticoagulation. Use Caution/Monitor.
parecoxib
Monitor Closely (1)parecoxib and American ginseng both increase anticoagulation. Use Caution/Monitor.
pau d'arco
Monitor Closely (1)American ginseng and pau d'arco both increase anticoagulation. Use Caution/Monitor.
phenindione
Monitor Closely (1)phenindione and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
phentermine
Minor (1)American ginseng increases effects of phentermine by pharmacodynamic synergism. Minor/Significance Unknown.
phytoestrogens
Monitor Closely (1)American ginseng and phytoestrogens both increase anticoagulation. Use Caution/Monitor.
pioglitazone
Minor (1)American ginseng increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown.
piroxicam
Monitor Closely (1)piroxicam and American ginseng both increase anticoagulation. Use Caution/Monitor.
protamine
Monitor Closely (1)protamine and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
reishi
Monitor Closely (1)American ginseng and reishi both increase anticoagulation. Use Caution/Monitor.
repaglinide
Minor (1)American ginseng increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown.
reteplase
Monitor Closely (1)reteplase and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
rosiglitazone
Minor (1)American ginseng increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown.
salicylates (non-asa)
Monitor Closely (1)salicylates (non-asa) and American ginseng both increase anticoagulation. Use Caution/Monitor.
salsalate
Monitor Closely (1)salsalate and American ginseng both increase anticoagulation. Use Caution/Monitor.
saxagliptin
Minor (1)American ginseng increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown.
serdexmethylphenidate/dexmethylphenidate
Minor (1)American ginseng increases effects of serdexmethylphenidate/dexmethylphenidate by pharmacodynamic synergism. Minor/Significance Unknown.
Siberian ginseng
Monitor Closely (1)American ginseng and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.
sitagliptin
Minor (1)American ginseng increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown.
sulfasalazine
Monitor Closely (1)sulfasalazine and American ginseng both increase anticoagulation. Use Caution/Monitor.
sulindac
Monitor Closely (1)sulindac and American ginseng both increase anticoagulation. Use Caution/Monitor.
tenecteplase
Monitor Closely (1)tenecteplase and American ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
tolazamide
Minor (1)American ginseng increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown.
tolbutamide
Minor (1)American ginseng increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown.
tolfenamic acid
Monitor Closely (1)tolfenamic acid and American ginseng both increase anticoagulation. Use Caution/Monitor.
tolmetin
Monitor Closely (1)tolmetin and American ginseng both increase anticoagulation. Use Caution/Monitor.
vildagliptin
Minor (1)American ginseng increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown.
yohimbine
Minor (1)American ginseng increases effects of yohimbine by pharmacodynamic synergism. Minor/Significance Unknown.

Frequency Not Defined

Allergic skin reactions

Diarrhea

Headache

HTN

Insomnia

Itching

Increased libido

Nervousness

Palpitations

Vaginal bleeding

Contraindications

Hypertension, pregnancy

Breast CA, endometrial CA, endometriosis, hemorrhage, hormone sensitive conditions, ovarian CA, thrombosis, uterine fibroids

Avoid prior to surgery: may cause bleeding

Cautions

Bleeding disorders, cardiac disorders, diabetes mellitus, hypotension, insomnia, schizophrenia

Pregnancy & Lactation

Pregnancy Category: N/A

Lactation: N/A

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Mechanism of Action

Ginsenosides have various metabolic effects

Metabolism: N/A

Excretion: N/A

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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