Androstenedione (Herb/Suppl)

Brand and Other Names:

Suggested Dosing

Improving muscle strength & size

50-150 mg PO BID

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Suggested Uses

Improve strength, athletic performance

Efficacy

Demonstrated to increase endogenous testosterone production, but no conclusive effects on muscle mass

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Interactions

Interaction Checker

and Androstenedione

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (0)

                  Minor (15)

                  • bazedoxifene/conjugated estrogens

                    androstenedione increases effects of bazedoxifene/conjugated estrogens by pharmacodynamic synergism. Minor/Significance Unknown.

                  • conjugated estrogens

                    androstenedione increases effects of conjugated estrogens by pharmacodynamic synergism. Minor/Significance Unknown.

                  • conjugated estrogens, vaginal

                    androstenedione increases effects of conjugated estrogens, vaginal by pharmacodynamic synergism. Minor/Significance Unknown.

                  • danazol

                    androstenedione increases effects of danazol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • estradiol

                    androstenedione increases effects of estradiol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • estrogens conjugated synthetic

                    androstenedione increases effects of estrogens conjugated synthetic by pharmacodynamic synergism. Minor/Significance Unknown.

                  • estropipate

                    androstenedione increases effects of estropipate by pharmacodynamic synergism. Minor/Significance Unknown.

                  • fluoxymesterone

                    androstenedione increases effects of fluoxymesterone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • mesterolone

                    androstenedione increases effects of mesterolone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • mestranol

                    androstenedione increases effects of mestranol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • oxandrolone

                    androstenedione increases effects of oxandrolone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • oxymetholone

                    androstenedione increases effects of oxymetholone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • testosterone

                    androstenedione increases effects of testosterone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • testosterone buccal system

                    androstenedione increases effects of testosterone buccal system by pharmacodynamic synergism. Minor/Significance Unknown.

                  • testosterone topical

                    androstenedione increases effects of testosterone topical by pharmacodynamic synergism. Minor/Significance Unknown.

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                  Adverse Effects

                  Expected to be similar to exogenous testosterone:

                  Men: acne, decreased endogenous testosterone, testicular atrophy, gynecomastia, increased risk of prostate cancer

                  Women: clitoral hypertrophy, hirsutism, acne, amenorrhea

                  Adolescents: early closing of growth plates, decreased adult height

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                  Warnings

                  Contraindications

                  N/A

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                  Pregnancy & Lactation

                  Pregnancy Category: N/A

                  Lactation: N/A

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

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                  Pharmacology

                  Metabolism: N/A

                  Excretion: N/A

                  Mechanism of Action

                  Precursor of estrone and testosterone

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                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.